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        <key_dates>
            <deposition>2024-02-06</deposition>
            <header_release>2025-12-31</header_release>
            <map_release>2025-12-31</map_release>
            <update>2025-12-31</update>
        </key_dates>
        <grant_support>
            <grant_reference>
                <funding_body>National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)</funding_body>
                <code>R21-AI167756</code>
                <country>United States</country>
            </grant_reference>
            <grant_reference>
                <funding_body>National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)</funding_body>
                <code>U54-AI170856</code>
                <country>United States</country>
            </grant_reference>
        </grant_support>
        <title>HIV-1 R18L CA hexamer</title>
        <authors_list>
            <author>Schirra RT</author>
            <author>Pornillos O</author>
            <author>Ganser-Pornillos BK</author>
        </authors_list>
        <keywords>capsid, VIRUS LIKE PARTICLE</keywords>
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        <citation_list>
            <primary_citation>
                <journal_citation published="true">
                    <author order="1">Schirra RT</author>
                    <author ORCID="0000-0002-1353-4613" order="2">Dos Santos NFB</author>
                    <author order="3">Ganser-Pornillos BK</author>
                    <author order="4">Pornillos O</author>
                    <title>Arg18 Substitutions Reveal the Capacity of the HIV-1 Capsid Protein for Non-Fullerene Assembly.</title>
                    <journal_abbreviation>Viruses</journal_abbreviation>
                    <country>CH</country>
                    <volume>16</volume>
                    <year>2024</year>
                    <external_references type="PUBMED">39066201</external_references>
                    <external_references type="DOI">doi:10.3390/v16071038</external_references>
                    <external_references type="ISSN">1999-4915</external_references>
                </journal_citation>
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                <accession_id>EMD-43641</accession_id>
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            </db_reference>
            <db_reference>
                <db_name>PDB</db_name>
                <accession_id>8vxw</accession_id>
                <content_type>unspecified</content_type>
                <details>HIV-1 R18L CA pentamer</details>
            </db_reference>
        </other_db_list>
    </crossreferences>
    <sample>
        <name>HIV-1 CA R18L hexamer from capsid-like particles assembled in 1 M NaCl</name>
        <supramolecule_list>
            <complex_supramolecule supramolecule_id="1">
                <name>HIV-1 CA R18L hexamer from capsid-like particles assembled in 1 M NaCl</name>
                <parent>0</parent>
                <macromolecule_list>
                    <macromolecule>
                        <macromolecule_id>1</macromolecule_id>
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                </macromolecule_list>
                <natural_source database="NCBI">
                    <organism ncbi="11676">Human immunodeficiency virus 1</organism>
                </natural_source>
            </complex_supramolecule>
        </supramolecule_list>
        <macromolecule_list>
            <protein_or_peptide macromolecule_id="1">
                <name>Capsid protein p24</name>
                <natural_source database="NCBI">
                    <organism ncbi="11676">Human immunodeficiency virus 1</organism>
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                <molecular_weight>
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                <number_of_copies>1</number_of_copies>
                <recombinant_expression database="NCBI">
                    <recombinant_organism ncbi="469008">Escherichia coli BL21(DE3)</recombinant_organism>
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                <enantiomer>LEVO</enantiomer>
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                    <string>PIVQNLQGQMVHQAISPLTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEW
DRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEP
FRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPGATLEEMMTACQGVGGPGHKARVL</string>
                    <external_references type="UNIPROTKB">P12497</external_references>
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