2025-12-31 REL RCSB INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY RCSB RCSB 2024-06-19 2025-12-31 2025-12-31 2025-12-31 Australian Research Council (ARC) DP220101681 Australia Australian Research Council (ARC) DP170104484 Australia Yersinia entomophaga holotoxin complex in pore conformation Low YS Landsberg MJ Toxin, pore-forming, insecticidal, chitinases Low YS Roche SG Aleksandrova NA Foley G Low JK Box JK Croll TI Chassagnon IR Lott JS Deplazes E Boden M Hurst MR Piper SJ Landsberg MJ Complete structures of the YenTc holotoxin prepore and pore reveal the evolutionary basis for chitinase incorporation into ABC toxins. Nat Commun UK 16 11121 11121 2025 41397958 doi:10.1038/s41467-025-66050-x 2041-1723 9cbc FULLOVERLAP PDB 9C4k unspecified
Yersinia entomophaga holotoxin complex in prepore conformation
 EMDB EMD-45422 associated EM volume
Yersinia entomophaga holotoxin complex in pore conformation
 Yersinia entomophaga holotoxin complex in pore conformation Yersinia entomophaga holotoxin complex in pore conformation 0 1 2 3 4 5 Yersinia entomophaga 2.5 Toxin subunit YenA1 Yersinia entomophaga 0.12991232 5 LEVO MDKYNNYSNVIKNKSSISPLLAAAAKIEPEITVLSSASKSNRSQYSQSLADTLLGLGYRSIFDIAKVSRQRFIKRHDESL LGNGAVIFDKAVSMANQVLQKYRKNRLEKSNSPLVPQTSSSTDASSESQTNKLPEYNQLFPEPWDNFCRPGAIEALDSPA SYLLDLYKFIQSVELDGSNQARKLETRRADIPKLSLDNDALYKEVTALSIVNDVLSGSAREYIDQSGQADKAVNQILGDT HFPFTLPYSLPTQQINKGLGASNIELGTVIQRVDPQFSWNTTQEKYNQVLLAYTQLSSEQIALLSLPDVFTQNFLTQTEL SAGYLSASTTEILAEKDLSRHGYIVKAADNIKGPTQLVEHSDASYDVIELTCTNQAKETITVKLRGENIITYQRTKARMV PFDNSSPFSRQLKLTFVAEDNPSLGNLDKGPYFANMDIYAAEWVRENVSSETMVSRPFLTMTYRIAIAKAGASLEELQPE ADAFFINNFGLSAEDSSQLVKLVAFGDQTGSKAEEIESLLSCGENLPIVSPNVIFANPIFGSYFNDEPFPAPYHFGGVYI NAHQRNAMTIIRAEGGREIQSLSNFRLERLNRFIRLQRWLDLPSHQLDLLLTSVMQADADNSQQEITEPVLKSLGLFRHL NLQYKITPEIFSSWLYQLTPFAVSGEIAFFDRIFNREQLFDQPFILDGGSFTYLDAKGSDAKSVKQLCAGLNISAVTFQF IAPLVQSALGLEAGTLVRSFEVVSSLYRLVSIPQTFGLSTEDGLILMNILTDEMGYLAKQPAFDDKQTQDKDFLSIILKM EALSAWLTKNNLTPASLALLLGVTRLAVVPTNNMVTFFKGIANGLSENVCLTTDDFQRQELEGADWWTLLSTNQVIDDMG LVLDIHPVWGKSDEEMLMEKIQSIGVSNDNNTLSIIVQILIQAKNAQENLLSQTISAEYGVERSVVPLQLRWLGSNVYSV LNQVLNNTPTDISSIVPKLSELTYSLLIYTQLINSLKLNKEFIFLRLTQPNWLGLTQPKLSTQLSLPEIYLITCYQDWVV NANKNEDSIHEYLEFANIKKTEAEKTLVDNSEKCAELLAEILAWDAGEILKAASLLGLNPPQATNVFEIDWIRRLQTLSE KTMISTEYLWQMGDLTENSEFSLKEGVGEAVMAALKAQGDSDNV B6A877 Toxin subunit YenA2 Yersinia entomophaga 0.156324938 5 LEVO MSNSIEAKLQEDLRDALVDYYLGQIVPNSKDFTNLRSTIKNVDDLYDHLLLDTQVSAKVITSRLSLVTQSVQQYINRIAL NLEPGLSINQQEATDWEEFANRYGYWAANQQLRMFPEIYVDPTLRLTKTEFFFQLESALNQGKLTDDVAQKAVLGYLNNF EEVSNLEIIAGYQDGIDIENDKTYFVARTRMQPYRYFWRSLDASQRNANSQELYPTAWSEWKAISVPLENVANGIVRPIM MDNRLYISWFEVAEEKETDSDGNIIVSGRYRTKIRLAHLGFDGVWSSGTTLREEVLADQMEEMIAVVDRMEDEPRLALVA FKEMSESWDVVFSYICDSMLIESSNLPTTTHPPKPGDGDKGLSDLDDYGANLVWFYLHETANGGKAEYKQLILYPVIINR DWPIELDKTHQGDFGTVDDFTLNSNYTGDELSLYLQSSSTYKYDFSKSKNIIYGIWKEDANNNRCWLNYKLLTPEDYEPQ INATLVMCDKGDVNIITGFSLPNGGVDAGGKIKVTLRVGKKLRDKFQIKQFSQTQYLQFPEASSADVWYIGKQIRLNTLF AKELIGKASRSLDLVLSWETQNSRLEEAILGGAAELIDLDGANGIYFWELFFHMPFMVSWRFNVEQRYEDANRWVKYLFN PFECEDEPALLLGKPPYWNSRPLVDEPFKGYSLTQPSDPDAIAASDPIHYRKAVFNFLTKNIIDQGDMEYRKLQPSARTL ARLSYSTASSLLGRRPDVQLTSFWQPLTLEDASYKTDSEIRAIEMQSQPLTFEPVVHDQTMSAVDNDIFMYPMNNELRGL WDRIENRIYNLRHNLTLDGKEINMDLYDSSISPRGLMKQRYQRVVTARNASKMNFKVPNYRFEPMLNRSKSGVETLIQFG STLLSLLERKDSLSFDAYQMIQSGDLYRFSIDLQQQDIDINKASLEALQVSKQSAQDRYDHFKELYDENISSTEQKVIEL QSQAANSLLMAQGMRTAAAALDVIPNIYGLAVGGSHWGAPLNAAAEIIMIKYQADSSKSESLSVSESYRRRRQEWELQYK QAEWEVNSVEQQINLQNMQIKAANKRLEQVEAQQQQAMALLDYFSERFTNESLYTWLISQLSSLYLQAYDAVLSLCLSAE ASLLYELNLGEQSFVGGGGWNDLYQGLMAGETLKLALMRMERVYVEQNSRRQEITKTISLKALLGESWPAELNKLKQKTP INFNLEEQIFVEDYQELYQRRIKSVSVSLPMLVGPYEDVCAQLTQTSSSYSTRADLKTVENMLTKRTFADTPHLVRSIQP NQQISLSTGVNDSGLFMLNFDDERFLPFEGSGVDSSWRLQFTNLKQNLDSLNDVILHVKYTAAIGSSTFSQGVRKILANI NNDE B6A878 Chitinase 2 Yersinia entomophaga 0.069740609 5 LEVO MVNKYTYTSSKAMSDISDVIGEPLAAWDSQVGGRVFNVIFDGKVYTNTYWVERWQVPGIGSSDGNPHNAWKFVRAATADE INKIGNPTTADVKPTENIPSPILVEDKYTEETYSRPDVNFKEDGSQGNLSYTATRVCAPMYNHYVGDKTKPKLSAYITDW CQYDARLDGGGSKEEERGRGFDLATLMQNPATYDRLIFSFLGICGDIGNKSKKVQEVWDGWNAQAPSLGLPQIGKGHIVP LDPYGDLGTARNVGLPPESADTSIESGTFLPYYQQNRAAGLLGGLRELQKKAHAMGHKLDLAFSIGGWSLSSYFSALAEN PDERRVFVASVVDFFVRFPMFSCVDIDWEYPGGGGDEGNISSDKDGENYVLLIKELRSALDSRFGYSNRKEISIACSGVK AKLKKSNIDQLVANGLDNIYLMSYDFFGTIWADYIGHHTNLYSPKDPGEQELFDLSAEAAIDYLHNELGIPMEKIHLGYA NYGRSAVGGDLTTRQYTKNGPALGTMENGAPEFFDIVKNYMDAEHSLSMGKNGFVLMTDTNADADFLFSEAKGHFISLDT PRTVKQKGEYAAKNKLGGVFSWSGDQDCGLLANAAREGLGYVADSNQETIDMGPLYNPGKEIYLKSISEIKSK B6A879 3.2.1.14 Toxin subunit YenB Yersinia entomophaga 0.167147984 1 LEVO MQNSQEMAITTLSLPKGGGAINGMGESVGQAGPDGMVTFSIPLPFSAGRGVAPALSLSYSSGAGNGPFGMGWQCSAMSIS RRTQKGVPQYNEDDEFLSPSGEVMAIALNDSGFEDVRTANRLQGIPLPFSYKVTRYQPRLIQDFIKIEYWQPVKQTDGTP FWIIYSPDGQTHILGKNSHSRVANAENPSQIASWLLEETVTPTGEHIYYQYSGENQVNCTDAEIALHPQDSAQRYLARID YGNISPQASLFVLDEELPNLTQWLFHLVFDYGERDISINKIPTFEGGTTGWLARPDMFSRYDFGIEIRNRRLCHQVLGFH RLEALNDRDVTDEIPVLVNRLTLDYDLNNSVSTLVAVRQVAYETDGSPITQPPLEFDYQRFDTGSIPGWQEMPQLEAFNG YQPYQMIDLYGEGTPGILYQETPGAWWYKSPQRQIGGDSNAVTYGAMKALPKIPRLQEGATLMDINGDGRLDWVITSAGV RGFHSIHSTGEWTHFTPLNTLPTEYFHPKAQLADLVGAGLSDLVLIGPKSVRLYANQQGNWAPAQDVTQAENVSLPVIGI DSRQLVAFADMLGSGQQHLVEITADSVKCWPNMGHGRFGQPLTLEGFSQPQTSFNPDRVFLADIDGSGTNDIIYAHSECL EIYLNESGNRFSKPISLLLPDGVNFDNTCQLQAADIQGLGIASLVMTVPHMSPTHWRCDLALNKPWLLNVMNNNRGAETC LFYRSSAQFWLDEKQLVEAAGQQPECHLPFPMHLHWRSEIFDEITGNRLTQEQEYAHGSWDGQEREFRGFGRLIQRDTDG FAQGTVDIPTHPSRTVSWFATGIPEIDTTLSAEFWRGDDQAFSPFSPRFTRWENDSEAGSDVAFIPSEHDAFWLNRAMKG QLLRSELYGDDGTPEAEIPYSVTEMRHQVRALPTTDATVPSAWCSTIETRSYQYQRVAADPQCSQQVVIKADRYGSPLLS VAINYPRRKKPEKSPYPDDLPETLFDSSYDTQQQQLHLTKQQQNYFHLTNDDNWLLGLPKEQRNDGYQYDQERAPANGFT LETLIASNSLIGSNQPFTYLGQSRVAYQGGVDEQPSLQALVAYGETAILDEKTLQAFVGVLDSKTRDELLFSAGYQLAPR LFRVESEPDVWVARQGYSEFGDYSQFWRPLSQRSTLLTGKTTLKWDKHYCVVIETQDAAQLVTQARYDYRFLTPYSLTDA NDNQHYVVLNPFGEVIASRFWGTEAGKDAGYSTPQAKPFVVPATIEAALALSPGIPVAHCAIFEPESWMQKLTQHDVSER MADNGTLWNALLQARFVTEDGYVCALGRRRWMARHGLSVLMLTLLAEIPRTPPHSLTITTDRYDSDDQQQLRQRILFSDG FGRLLQSAQRVEAGESWQRSEDSSLVVNVSGTPALVVTDNRWAVSGRTEYDGKGQGIRVYQPYFLDDWRYLSDDSARTDL FADTHIYDPLGREYQVITAKGYRRERQYTPWFVVNQDENDTAANLAI B6A880 Toxin subunit YenC2 Yersinia entomophaga 0.10756387499999999 1 LEVO MDIQLFSKTPSVTVFDNRGLSVRDIAYRRHPDTPKVTEECITYHQFDFRGFLAQSLDPRLNHKEVTNFSYLTDLNGNIIY TQSVDAGNTLVLNDTEGRSVIAMTNISRGENGKDDLSLAVTRTFQYENAPLPGRPLSVTEQVNGENARITEHFVYAGNTP QEKNLNLAGQCVSYYDAAGLIQTDSVSLTGKPLSVSRKLLKNLDDTNILADWQGNDTSAWNSLLATEIYTTVTRTDAAGA VLTTIDAVGNQQRVAFDIAGQLSASWLTLKGGQEQVIIKVLTYSAAGQKLREEGGNGVVTTYTYEAETQRLIGIKTERPN GHAAGAKVLQDLRYEYDPVGNVLSITNDAEETRFWRNQKVVPENAYRYDSLYQLVSASGREVAGAGQQGSDLPSPLVPLP SDSSVYTNYTRTYTYDSAGNLMRIRHSAPATNNNYTLNITVSERSNRGVMSSLTENPADVDALFTASGSQKCLQQGQSLI WTPRGELRTVLLVARGETADDSESYRYDGSSQRILKISSQQTNHSARVQRALYLPGLEWRTMTGGVAEAENLQVICIGEA GRAQVRVLHWESGKPDGIINDQIRWSYDNLTCSSGLEVDGDGLVISMEEYYPYGGTAVWAARSHIETAYKTVRYSGKERD ATGLYYYGFRYYQPWAGRWLSADPAGTVDGLNLYRMVRNNPLRLTDPDGMAPLDWLDLDTTNASRDIVKAIYQLNQIDGP HRGVRDTYQRMTESTGMILQETLNNEAVLKGIKQKDKEKKSRGMKFTNSKLKTYAAHAGVLNTLQPDPVYKDGFLNLPGS LGNKNTFPGVELIEDKVKPSLSQYHPDKLGKSQRWKPESSLGYYRVADTEAFITGIRSQYKSSGTDLHAVVEGRIRDHLL ANNNVLPKMAGIAGLHAEVQALNYIISNPDIEGGNAERLNGSYIFTQRLVGDVNQDFPACYNCSGIISGLENVMTGRVNN DVRLKRRKSF B6A882 singleParticle particle 7.0 Quantifoil R2/2 COPPER CARBON GLOW DISCHARGE ETHANE FEI TECNAI F30 FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 1.8 3.0 SIDE ENTRY, EUCENTRIC NITROGEN GATAN K2 SUMMIT (4k x 4k) 45.0 1 cryoSPARC PHASE FLIPPING AND AMPLITUDE CORRECTION 6OGD C1 6.43 FSC 0.143 CUT-OFF cryoSPARC 23515 MAXIMUM LIKELIHOOD cryoSPARC MAXIMUM LIKELIHOOD cryoSPARC emd_45422.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 256 256 256 0 0 0 256 256 256 743.04004 743.04004 743.04004 90.0 90.0 90.0 X Y Z -1.39713 3.3658323 -0.0016022038 0.12145652 2.9025002 2.9025002 2.9025002 0.5 AUTHOR 6OGD PDB experimental model AB INITIO MODEL emd_45422_msk_1.map emd_45422_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 256 256 256 0 0 0 256 256 256 743.04004 743.04004 743.04004 90.0 90.0 90.0 X Y Z -1.2426043 2.546653 0.0009546222 0.17645237 2.9025002 2.9025002 2.9025002 AUTHOR emd_45422_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 256 256 256 0 0 0 256 256 256 743.04004 743.04004 743.04004 90.0 90.0 90.0 X Y Z -1.1472124 2.526138 0.0009503436 0.17618674 2.9025002 2.9025002 2.9025002 AUTHOR