2025-11-12 REL RCSB RCSB RCSB 2024-09-25 2025-11-12 2025-11-12 2025-11-12 National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) United States Cryo-EM map of the human TREX-2.1 complex bound to DDX39B(UAP56) Clarke BP Xie Y Ren Y mRNA nuclear export, TREX, TREX-2, LENG8, UAP56, DDX39B, RNA BINDING PROTEIN Clarke BP Gao S Mei M Xie D Angelos AE Vazhavilla A Hill PS Cagatay T Batten K Shay JW Xie Y Fontoura BMA Ren Y Structural mechanism of DDX39B regulation by human TREX-2 and a related complex in mRNP remodeling. Nat Commun UK 16 5471 5471 2025 40595470 doi:10.1038/s41467-025-60547-1 2041-1723 PDB 9DLV unspecified
EM maps from the same dataset
 EMDB EMD-47126 associated EM volume human TREX-2.1 complex(LENG8/PCID2/DSS1) and DDX39B human TREX-2.1 complex(LENG8/PCID2/DSS1) and DDX39B 0 1 2 3 4 Homo sapiens singleParticle particle 8.0 ETHANE TFS KRIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 0.8 2.0 GATAN K3 (6k x 4k) 56.1 1 PHASE FLIPPING AND AMPLITUDE CORRECTION
AlphaFold model
 3.28 FSC 0.143 CUT-OFF 191817 MAXIMUM LIKELIHOOD MAXIMUM LIKELIHOOD emd_47126.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 288 288 288 0 0 0 288 288 288 236.16 236.16 236.16 90.0 90.0 90.0 X Y Z -0.2253759 0.36625165 -0.00027190786 0.00935098 0.82 0.82 0.82 0.04 AUTHOR Cryo-EM map of the human TREX-2.1 complex bound to DDX39B(UAP56) emd_47126_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 288 288 288 0 0 0 288 288 288 236.16 236.16 236.16 90.0 90.0 90.0 X Y Z -0.26570758 0.4640599 0.00008702984 0.018605625 0.82 0.82 0.82 AUTHOR Half Map A emd_47126_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 288 288 288 0 0 0 288 288 288 236.16 236.16 236.16 90.0 90.0 90.0 X Y Z -0.28564605 0.521475 0.00009120576 0.018533036 0.82 0.82 0.82 AUTHOR Half Map B