2026-03-11 REL RCSB INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY RCSB RCSB 2025-02-26 2026-03-11 2026-03-11 2026-03-11 National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) 75N93019C00052 United States Computationally optimized broadly reactive influenza B hemagglutinin BC2 bound by antibody #3978 Dzimianski JV Kunkel I Balasco Serrao VH DuBois RM influenza, antibody, cell entry, hemagglutination, VIRAL PROTEIN, VIRAL PROTEIN-Immune System complex Dzimianski JV Kunkel I Balasco Serrao VH DuBois RM Computationally optimized broadly reactive influenza B hemagglutinin BC2 bound by antibodies #46 and #3978 To Be Published 0353 EMD-49463 other EM volume 9nj6 FULLOVERLAP PDB 9NJ3 unspecified EMDB EMD-49463 other EM volume EMDB EMD-49475 associated EM volume
Computationally optimized broadly reactive influenza B hemagglutinin BC2 bound by antibody #3978
 Complex of a viral protein with an antibody Complex of a viral protein with an antibody 0 1 2 3 Homo sapiens Hemagglutinin Influenza B virus 0.05737524199999999 3 Cricetulus griseus LEVO DRICTGITSSNSPHVVKTATQGEVNVTGVIPLTTTPTKSHFANLKGTKTRGKLCPKCLNCTDLDVALGRPKCMGTIPSAK ASILHEVRPVTSGCFPIMHDRTKIRQLPNLLRGYENIRLSTHNVINAEKAPGGPYRIGTSGSCPNVTNGNGFFATMAWAV PKNDNNKTATNPLTVEVPYICTEGEDQITVWGFHSDNETQMKKLYGDSKPQKFTSSANGVTTHYVSQIGGFPNQTEDGGL PQSGRIVVDYMVQKSGKTGTIVYQRGILLPQKVWCASGRSKVIKGSLPLIGEADCLHEKYGGLNKSKPYYTGEHAKAIGN CPIWVKTPLKLANGTKYRPPAKLLKERGFFGAIAGFLEGGWEGMIAGWHGYTSHGAHGVAVAADLKSTQEAINKITKNLN SLSELEVKNLQRLSGAMDELHNEILELDEKVDDLRADTISSQIELAVLLSNEGIINSEDEHLLALERKLKKMLGPSAVDI GNGCFETKHKCNQTCLDRIAAGTFNAGEFSLPTFDSLNITAASSGRLVPR P17504 Fab A Heavy Chain Homo sapiens 0.025610729 3 Cricetulus griseus LEVO EVQLVESGGHLVQPGGSLRLSCEASGFSFDEYAMHWVREAPGKGLEWVAGISWNSGAIGYAGSVKGRFTISKDSAKRVLY LQMNSLRPEDAALYYCAKDMREGCSGTNCYSYYYYFYAMDVWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCL VKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTH Fab A Light Chain Homo sapiens 0.022896276999999996 3 Cricetulus griseus LEVO QSVLTQPPSVSGAPGQGVTISCTGSSSNLGADYDVHWYQHLPGKAPKLLIYDNDKRPPGIPDRFSASRSGPSASLAISGL QGEDEADYYCQSYDSHLSGSVFGGGTKLTVVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSP VKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTEC 2-acetamido-2-deoxy-beta-D-glucopyranose 0.000221208 3 NAG singleParticle particle 7.4 ETHANE 100 298 FEI VITROBOT MARK IV TFS KRIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 0.5 2.8000000000000003 FEI TITAN KRIOS AUTOGRID HOLDER NITROGEN GATAN K3 BIOCONTINUUM (6k x 4k) 2 35025 50.0 1 1165223 cryoSPARC 4.5.3 PHASE FLIPPING AND AMPLITUDE CORRECTION 1 C3 2.36 FSC 0.143 CUT-OFF cryoSPARC 4.5.3 185640 ANGULAR RECONSTITUTION cryoSPARC 4.5.3 ANGULAR RECONSTITUTION cryoSPARC 4.5.3 4 cryoSPARC 4.5.3 emd_49475.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 576 576 576 0 0 0 576 576 576 329.8752 329.8752 329.8752 90.0 90.0 90.0 X Y Z -1.79456 3.015668 -0.0002298655 0.036777884 0.5727 0.5727 0.5727 0.2 AUTHOR sharpened map after spIsoNet correction 9NJ3 A PDB experimental model 9NJ3 H PDB experimental model 9NJ3 L PDB experimental model RIGID BODY FIT emd_49475_msk_1.map emd_49475_additional_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 576 576 576 0 0 0 576 576 576 329.8752 329.8752 329.8752 90.0 90.0 90.0 X Y Z -0.33666366 0.73095405 -0.00055743026 0.011792622 0.5727 0.5727 0.5727 AUTHOR unsharpened map emd_49475_additional_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 576 576 576 0 0 0 576 576 576 329.8752 329.8752 329.8752 90.0 90.0 90.0 X Y Z -0.3289352 0.90951633 0.0000051082493 0.021848593 0.5727 0.5727 0.5727 AUTHOR spIsoNet corrected half map B emd_49475_additional_3.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 576 576 576 0 0 0 576 576 576 329.8752 329.8752 329.8752 90.0 90.0 90.0 X Y Z -0.32379645 0.9235727 0.0000020562857 0.02188176 0.5727 0.5727 0.5727 AUTHOR spIsoNet corrected half map A emd_49475_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 576 576 576 0 0 0 576 576 576 329.8752 329.8752 329.8752 90.0 90.0 90.0 X Y Z -0.3797164 0.78816074 0.0000051081715 0.021848613 0.5727 0.5727 0.5727 AUTHOR half map B emd_49475_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 576 576 576 0 0 0 576 576 576 329.8752 329.8752 329.8752 90.0 90.0 90.0 X Y Z -0.37812215 0.80129474 0.0000020559125 0.021881811 0.5727 0.5727 0.5727 AUTHOR half map A