2026-03-11 REL PDBe INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY PDBe PDBe 2025-05-21 2026-03-11 2026-03-11 2026-03-11 Canadian Institutes of Health Research (CIHR) Canada Helmholtz Association Germany A53T alpha-synuclein fibril - Type 2 So RWL Frieg B Schroeder GF Watts JC alpha-synuclein, fibril, A53T mutant, PROTEIN FIBRIL So RWL Frieg B Camino JD Situ C Metri MN Silver NRG Li LY Mao A Stuart E Schroder GF Watts JC Stochastic misfolding drives the emergence of distinct alpha-synuclein strains. Neuron US 2026 41763203 doi:10.1016/j.neuron.2026.01.014 0896-6273 2038 NERNET 9rb6 FULLOVERLAP PDB 9RB3 unspecified
A53T alpha-synuclein fibril - Type 1
 EMDB EMD-53885 associated EM volume
A53T alpha-synuclein fibril - Type 2
 A53T alpha-synuclein fibril - Type 2 A53T alpha-synuclein fibril - Type 2 0 1 Homo sapiens Alpha-synuclein Homo sapiens 0.014506136 10 Escherichia coli BL21(DE3) LEVO MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVTTVAEKTKEQVTNVGGAVVTGVTAVAQK TVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA P37840 helical filament 7.4 ETHANE TFS KRIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 0.5 2.5 GATAN K3 BIOQUANTUM (6k x 4k) 35.0 1 2.38 179.31 C1 3.02 FSC 0.143 CUT-OFF 15594 NONE
Featureless cylinder
 NOT APPLICABLE emd_53885.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 300 300 300 0 0 0 300 300 300 250.8 250.8 250.8 90.0 90.0 90.0 X Y Z -0.08110369 0.16184105 0.0010158769 0.009622928 0.836 0.836 0.836 0.04 AUTHOR A53T alpha-synuclein fibril - Type 2 emd_53885_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 300 300 300 0 0 0 300 300 300 250.8 250.8 250.8 90.0 90.0 90.0 X Y Z -0.028227713 0.06744808 0.00077388296 0.0048100445 0.836 0.836 0.836 AUTHOR A53T alpha-synuclein fibril - Type 2 (half map 2) emd_53885_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 300 300 300 0 0 0 300 300 300 250.8 250.8 250.8 90.0 90.0 90.0 X Y Z -0.03323035 0.07115698 0.00075356476 0.0047587175 0.836 0.836 0.836 AUTHOR A53T alpha-synuclein fibril - Type 2 (half map 1)