2026-03-25 REL PDBe INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY PDBe PDBe 2025-11-06 2026-03-25 2026-03-25 2026-03-25 Other private Cryo-EM structure of alphaM/beta2:MEM148-Fab headpiece complex (without alphaM I-domain) Lorentzen J Andersen GR phagocytosis, integrin, opsonisation, IMMUNE SYSTEM Lorentzen J Andersen GR Cryo-EM structure of alphaM/beta2:MEM148-Fab headpiece complex (without alphaM I-domain) To Be Published 0353 9t5z FULLOVERLAP EMDB EMD-55599 associated EM volume
Cryo-EM structure of alphaM/beta2:MEM148-Fab headpiece complex (without alphaM I-domain)
 Headpiece of alphaM/beta2 in complex with MEM148 Fab Headpiece of alphaM/beta2 in complex with MEM148 Fab 0 1 2 3 4
Headpiece of alphaM/beta2 in complex with MEM148 Fab-fragment from mouse IgG1
Homo sapiens 240 Integrin alpha-M Homo sapiens 0.08391283599999999 1 Homo sapiens LEVO FNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQRGSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAAT TSPPQLLACGPTVHQTCSENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTV MEQLKKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFRITNGARKNAFKILVVI TDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIE GTQTGSSSSFEHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRV QSLVLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPL PRGRTRWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKL SPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLH VQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKRSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFS LVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNTGGLEVLFQ P11215 Integrin beta-2 Homo sapiens 0.05221709399999999 1 Homo sapiens LEVO QECTKFKVSSCRECIESGPGCTWCQKLNFTGPGDPDSIRCDTRPQLLMRGCAADDIMDPTSLAETQEDHNGGQKQLSPQK VTLYLRPGQAAAFNVTFRRAKGYPIDLYYLMDLSYSMLDDLRNVKKLGGDLLRALNEITESGRIGFGSFVDKTVLPFVNT HPDKLRNPCPNKEKECQPPFAFRHVLKLTNNSNQFQTEVGKQLISGNLDAPEGGLDAMMQVAACPEEIGWRNVTRLLVFA TDDGFHFAGDGKLGAILTPNDGRCHLEDNLYKRSNEFDYPSVGQLAHKLAENNIQPIFAVTSRMVKTYEKLTEIIPKSAV GELSEDSSNVVHLIKNAYNKLSSRVFLDHNALPDTLKVTYDSFCSNGVTHRNQPRGDCDGVQINVPITFQVKVTATECIQ EQSFVIRALGFTDIVTVQVLPQCECRCRDQSRDRSLCHGKGFLECGICRCDTGYIGKNCEPAALQTLFQ P05107 Murine IgG1 MEM148 heavy chain Mus musculus 0.023865525000000002 1 Mus musculus LEVO EVQLQESGPSLVKPSQTLSLTCSVTGDSITSGYWNWIRKFPYNKLEYMGYISYSGSTYYNPSLESRVSITRDTSKNQYYL QLHSVTTEDTATYHCARERDYAFDFWGQGTTLTVSSAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSG SLSSGVHTFPAVLQSDLYTLSSSVTVPSSPRPSETVTCNVAHPASSTKVDKKIVPRDC Anti-colorectal carcinoma light chain Mus musculus 0.023936613 1 Mus musculus LEVO DIKMTQSPSPMYASLGERVTVTCKASQDINNYLSWFQQKPGKSPKTLIYRAKRLVDGVPSRFSGSGSGQDYSLTISSLEY EDMGIYYCLQYDEFPLTFGAGTKLELKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC CALCIUM ION 4.0078e-05 5 CA MANGANESE (II) ION 5.4938e-05 1 MN 2-acetamido-2-deoxy-beta-D-glucopyranose 0.000221208 2 NAG water 1.8015e-05 7 HOH singleParticle particle 0.15 7.5 0.02 C8H18N2O4S HEPES 0.15 NaCl sodium chloride 0.001 MnCl2 manganese chloride 2e-05 CaCl2 calcium chloride UltrAuFoil R0./1 GOLD 300 GOLD HOLEY GLOW DISCHARGE
25 mA current
 ETHANE 100 277 FEI VITROBOT MARK IV TFS KRIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 2.7 0.8 2.2 FEI TITAN KRIOS AUTOGRID HOLDER NITROGEN GIF Bioquantum 20 GATAN K3 (6k x 4k) 60.0 1 PHASE FLIPPING AND AMPLITUDE CORRECTION 3.1 FSC 0.143 CUT-OFF RELION 188421 RANDOM ASSIGNMENT MAXIMUM LIKELIHOOD emd_55599.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 350 350 350 0 0 0 350 350 350 452.90002 452.90002 452.90002 90.0 90.0 90.0 X Y Z -0.02337944 0.061809108 0.000003898602 0.00069897855 1.294 1.294 1.294 0.006 AUTHOR Consensus map (no Sharp) FLEXIBLE FIT REAL emd_55599_additional_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 350 350 350 0 0 0 350 350 350 452.90002 452.90002 452.90002 90.0 90.0 90.0 X Y Z -0.05216063 0.09983826 -0.00006050104 0.0017565148 1.294 1.294 1.294 AUTHOR Consensus map (Sharp) emd_55599_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 350 350 350 0 0 0 350 350 350 452.90002 452.90002 452.90002 90.0 90.0 90.0 X Y Z -0.027988384 0.06842773 -0.000060856997 0.0017500552 1.294 1.294 1.294 AUTHOR Half map 2 emd_55599_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 350 350 350 0 0 0 350 350 350 452.90002 452.90002 452.90002 90.0 90.0 90.0 X Y Z -0.031192392 0.067995146 -0.00006014503 0.0017423993 1.294 1.294 1.294 AUTHOR Half map 1