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    <admin>
        <current_status>
            <date>2025-08-13</date>
            <code>REL</code>
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        </current_status>
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            <deposition>2024-05-15</deposition>
            <header_release>2025-08-13</header_release>
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            <update>2025-08-13</update>
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        <grant_support>
            <grant_reference>
                <funding_body>National Natural Science Foundation of China (NSFC)</funding_body>
                <code>32301018</code>
                <country>China</country>
            </grant_reference>
        </grant_support>
        <title>Structure of nucleosome-bound RFX5 complex</title>
        <authors_list>
            <author>Xu K</author>
            <author>Zhang Y</author>
            <author>Yin Y</author>
            <author>Xue W</author>
            <author>Han Y</author>
            <author>Tian Y</author>
        </authors_list>
        <keywords>Nucleosome, histone, DNA, STRUCTURAL PROTEIN/DNA, STRUCTURAL PROTEIN-DNA complex</keywords>
    </admin>
    <crossreferences>
        <citation_list>
            <primary_citation>
                <journal_citation published="true">
                    <author order="1">Xue W</author>
                    <author order="2">Han Y</author>
                    <author order="3">Tian Y</author>
                    <author order="4">Wang J</author>
                    <author order="5">Xie Z</author>
                    <author order="6">Zheng X</author>
                    <author order="7">Yue X</author>
                    <author order="8">Dong S</author>
                    <author order="9">Li H</author>
                    <author order="10">Luo Z</author>
                    <author order="11">Zhang S</author>
                    <author order="12">Yang Y</author>
                    <author order="13">Zou Z</author>
                    <author order="14">Li W</author>
                    <author order="15">Ma N</author>
                    <author order="16">Zhu F</author>
                    <author ORCID="0000-0002-0128-7766" order="17">Chen C</author>
                    <author ORCID="0000-0002-5454-608X" order="18">Yin Y</author>
                    <author order="19">Zhang Y</author>
                    <author ORCID="0000-0001-7552-5002" order="20">Xu K</author>
                    <title>Structural basis of nucleosome binding and destabilization by the extended DNA binding domain of RFX5.</title>
                    <journal_abbreviation>Nucleic Acids Res.</journal_abbreviation>
                    <country>UK</country>
                    <volume>53</volume>
                    <year>2025</year>
                    <external_references type="PUBMED">40744500</external_references>
                    <external_references type="DOI">doi:10.1093/nar/gkaf734</external_references>
                    <external_references type="ISSN">1362-4962</external_references>
                    <external_references type="CSD">0389</external_references>
                    <external_references type="ASTM">NARHAD</external_references>
                </journal_citation>
            </primary_citation>
        </citation_list>
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                <details>Structure of nucleosome-bound RFX5 complex</details>
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    <sample>
        <name>free nucleosome</name>
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            <complex_supramolecule supramolecule_id="1">
                <name>free nucleosome</name>
                <parent>0</parent>
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                    <macromolecule>
                        <macromolecule_id>1</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>2</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>3</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>4</macromolecule_id>
                    </macromolecule>
                </macromolecule_list>
                <natural_source database="NCBI">
                    <organism ncbi="9606">Homo sapiens</organism>
                </natural_source>
            </complex_supramolecule>
        </supramolecule_list>
        <macromolecule_list>
            <protein_or_peptide macromolecule_id="1">
                <name>Histone H3.2</name>
                <natural_source database="NCBI">
                    <organism ncbi="9606">Homo sapiens</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.015543202999999998</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <recombinant_expression database="NCBI">
                    <recombinant_organism ncbi="469008">Escherichia coli BL21(DE3)</recombinant_organism>
                </recombinant_expression>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>GPMARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQD
FKTDLRFQSSAVMALQEASEAYLVGLFEDTNLAAIHAKRVTIMPKDIQLARRIRGERA</string>
                    <external_references type="UNIPROTKB">Q71DI3</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="2">
                <name>Histone H4</name>
                <natural_source database="NCBI">
                    <organism ncbi="9606">Homo sapiens</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.011824946</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <recombinant_expression database="NCBI">
                    <recombinant_organism ncbi="469008">Escherichia coli BL21(DE3)</recombinant_organism>
                </recombinant_expression>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MADLMSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEH
AKRKTVTAMDVVYALKRQGRTLYGFGG</string>
                    <external_references type="UNIPROTKB">P62805</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="3">
                <name>Histone H2A type 1-B/E</name>
                <natural_source database="NCBI">
                    <organism ncbi="9606">Homo sapiens</organism>
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                <molecular_weight>
                    <theoretical units="MDa">0.014319716</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <recombinant_expression database="NCBI">
                    <recombinant_organism ncbi="469008">Escherichia coli BL21(DE3)</recombinant_organism>
                </recombinant_expression>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>GPMSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR
IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK</string>
                    <external_references type="UNIPROTKB">P04908</external_references>
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            <protein_or_peptide macromolecule_id="4">
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                <natural_source database="NCBI">
                    <organism ncbi="9606">Homo sapiens</organism>
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                <molecular_weight>
                    <theoretical units="MDa">0.014351734</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <recombinant_expression database="NCBI">
                    <recombinant_organism ncbi="469008">Escherichia coli BL21(DE3)</recombinant_organism>
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                <enantiomer>LEVO</enantiomer>
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                    <string>MADLMPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAG
EASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK</string>
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                <name>DNA (147-MER)</name>
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(DT)(DC)(DT)(DT)(DC)(DC)(DG)(DA)(DT)(DC)(DT)(DT)(DG)(DG)(DT)(DT)(DA)(DG)(DG)(DG)
(DT)(DG)(DC)(DA)(DA)(DG)(DC)(DA)(DT)(DG)(DA)(DT)(DC)(DC)(DC)(DT)(DT)(DC)(DG)(DA)
(DT)(DG)(DA)(DA)(DT)(DA)(DG)(DA)(DG)(DC)(DC)(DG)(DA)(DC)(DT)(DG)(DG)(DG)(DC)(DA)
(DT)(DA)(DG)(DT)(DA)(DA)(DC)(DG)(DC)(DG)(DT)(DG)(DG)(DG)(DT)(DT)(DG)(DG)(DT)(DG)
(DA)(DG)(DG)(DT)(DG)(DG)(DT)(DT)(DC)(DA)(DC)(DG)(DG)(DT)(DC)(DA)(DT)(DG)(DC)(DC)
(DG)(DC)(DT)(DT)(DG)(DG)(DG)(DT)(DA)(DA)(DG)(DC)(DA)(DG)(DA)(DT)(DC)(DG)(DG)(DA)
(DA)(DG)(DA)(DG)(DG)(DA)(DT)</string>
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(DG)(DC)(DT)(DT)(DG)(DC)(DA)(DC)(DC)(DC)(DT)(DA)(DA)(DC)(DC)(DA)(DA)(DG)(DA)(DT)
(DC)(DG)(DG)(DA)(DA)(DG)(DA)(DG)(DC)(DG)(DT)(DC)(DG)(DT)(DG)(DT)(DA)(DA)(DC)(DG)
(DT)(DG)(DT)(DG)(DG)(DA)(DT)</string>
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                <classification>DNA</classification>
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                    <organism ncbi="9606">Homo sapiens</organism>
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                <molecular_weight>
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                <number_of_copies>1</number_of_copies>
                <recombinant_expression database="NCBI">
                    <recombinant_organism ncbi="469008">Escherichia coli BL21(DE3)</recombinant_organism>
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                <enantiomer>LEVO</enantiomer>
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