2026-02-04 REL PDBj INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY DATABASE_REFERENCES citation citation_author em_admin _citation.country _citation.journal_abbrev _citation.journal_id_ASTM _citation.journal_id_CSD _citation.journal_id_ISSN _citation.journal_volume _citation.page_first _citation.page_last _citation.pdbx_database_id_DOI _citation.pdbx_database_id_PubMed _citation.title _citation.year _em_admin.last_update EXPERIMENTAL_SUMMARY citation citation_author em_admin _citation.country _citation.journal_abbrev _citation.journal_id_ASTM _citation.journal_id_CSD _citation.journal_id_ISSN _citation.journal_volume _citation.page_first _citation.page_last _citation.pdbx_database_id_DOI _citation.pdbx_database_id_PubMed _citation.title _citation.year _em_admin.last_update PDBj PDBj 2024-09-27 2025-07-23 2025-07-23 2026-02-04 National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Disease (NIH/NIDDK) United States National Natural Science Foundation of China (NSFC) China CryoEM structure of mouse RAG SEC-2DNA Chen X Yao L Yang W Gellert M V(D)J recombination, RAG, PHD, Transposition, DNA BINDING PROTEIN, DNA BINDING PROTEIN-DNA complex Chen X Yao L Li W Ma S Yuan X Yang Y Yuan Y Liu Y Liu L Wang H Gellert M Yang W How RAG1/2 evolved from ancestral transposases to initiate V(D)J recombination without transposition. Proc.Natl.Acad.Sci.USA US 122 e2512362122 e2512362122 2025 40729386 doi:10.1073/pnas.2512362122 1091-6490 0040 PNASA6 EMD-61715 other EM volume EMD-61717 other EM volume 9jqn FULLOVERLAP PDB 9JPU unspecified PDB 9JPX unspecified EMDB EMD-61715 other EM volume EMDB EMD-61717 other EM volume EMDB EMD-61730 associated EM volume
CryoEM structure of mouse RAG SEC-12/23DNA
 mouse RAG SEC mouse RAG SEC 0 1 2 3 4 5 6 7 8 Mus musculus V(D)J recombination-activating protein 1 Mus musculus 0.11938935199999999 2 Homo sapiens LEVO MAASLPSTLSFSSAPDEIQHPQIKFSEWKFKLFRVRSFEKAPEEAQKEKDSSEGKPYLEQSPVVPEKPGGQNSILTQRAL KLHPKFSKKFHADGKSSDKAVHQARLRHFCRICGNRFKSDGHSRRYPVHGPVDAKTQSLFRKKEKRVTSWPDLIARIFRI DVKADVDSIHPTEFCHDCWSIMHRKFSSSHSQVYFPRKVTVEWHPHTPSCDICFTAHRGLKRKRHQPNVQLSKKLKTVLN HARRDRRKRTQARVSSKEVLKKISNCSKIHLSTKLLAVDFPAHFVKSISCQICEHILADPVETSCKHLFCRICILRCLKV MGSYCPSCRYPCFPTDLESPVKSFLNILNSLMVKCPAQDCNEEVSLEKYNHHVSSHKESKETLVHINKGGRPRQHLLSLT RRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQ YHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYD SALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKV FEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEA SGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGN AAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALR ELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEG NESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKSSGFTMNSKETLGDPLGIEDSLESQDSMEF P15919 3.1.-.- V(D)J recombination-activating protein 2 Mus musculus 0.05913841 2 Homo sapiens LEVO MSLQMVTVGHNIALIQPGFSLMNFDGQVFFFGQKGWPKRSCPTGVFHFDIKQNHLKLKPAIFSKDSCYLPPLRYPATCSY KGSIDSDKHQYIIHGGKTPNNELSDKIYIMSVACKNNKKVTFRCTEKDLVGDVPEPRYGHSIDVVYSRGKSMGVLFGGRS YMPSTQRTTEKWNSVADCLPHVFLIDFEFGCATSYILPELQDGLSFHVSIARNDTVYILGGHSLASNIRPANLYRIRVDL PLGTPAVNCTVLPGGISVSSAILTQTNNDEFVIVGGYQLENQKRMVCSLVSLGDNTIEISEMETPDWTSDIKHSKIWFGS NMGNGTIFLGIPGDNKQAMSEAFYFYTLRCSEEDLSEDQKIVSNSQTSTEDPGDSTPFEDSEEFCFSAEATSFDGDDEFD TYNEDDEDDESVTGYWITCCPTCDVDINTWVPFYSTELNKPAMIYCSHGDGHWVHAQCMDLEERTLIHLSEGSNKYYCNE HVQIARALQTPKRNPPLQKPPMKSLHKKGSGKVLTPAKKSFLRRLFD P21784 DNA (5'-D(P*AP*TP*TP*TP*GP*CP*AP*TP*CP*AP*CP*TP*GP*TP*G)-3') Escherichia coli 0.004574982 1 (DA)(DT)(DT)(DT)(DG)(DC)(DA)(DT)(DC)(DA)(DC)(DT)(DG)(DT)(DG) DNA DNA (5'-D(*CP*AP*CP*AP*GP*TP*GP*AP*TP*AP*CP*AP*GP*CP*C)-3') Escherichia coli 0.0045629880000000005 1 (DC)(DA)(DC)(DA)(DG)(DT)(DG)(DA)(DT)(DA)(DC)(DA)(DG)(DC)(DC) DNA DNA (5'-D(*CP*AP*CP*AP*GP*TP*GP*AP*TP*GP*CP*AP*AP*AP*T)-3') Escherichia coli 0.0046020240000000006 1 (DC)(DA)(DC)(DA)(DG)(DT)(DG)(DA)(DT)(DG)(DC)(DA)(DA)(DA)(DT) DNA DNA (5'-D(P*GP*GP*CP*TP*GP*TP*AP*TP*CP*AP*CP*TP*GP*TP*G)-3') Escherichia coli 0.0046159949999999995 1 (DG)(DG)(DC)(DT)(DG)(DT)(DA)(DT)(DC)(DA)(DC)(DT)(DG)(DT)(DG) DNA DNA (5'-D(*CP*AP*GP*GP*CP*CP*AP*GP*AP*TP*CP*CP*A)-3') Escherichia coli 0.003945588999999999 2 (DC)(DA)(DG)(DG)(DC)(DC)(DA)(DG)(DA)(DT)(DC)(DC)(DA) DNA DNA (5'-D(P*TP*GP*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*G)-3') Escherichia coli 0.003998595 2 (DT)(DG)(DG)(DA)(DT)(DC)(DT)(DG)(DG)(DC)(DC)(DT)(DG) DNA CALCIUM ION 4.0078e-05 2 CA ZINC ION 6.5409e-05 2 ZN singleParticle particle 7.4 ETHANE TFS KRIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 0.8 3.0 GATAN K2 SUMMIT (4k x 4k) 70.0 1
cryoSPARC
PHASE FLIPPING AND AMPLITUDE CORRECTION 3.03 FSC 0.143 CUT-OFF 144322 NOT APPLICABLE
cryoSPARC
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