2025-11-26 REL PDBj INITIAL_RELEASE REPOSITORY PDBj PDBj 2024-12-09 2025-11-26 2025-11-26 2025-11-26 Science and Engineering Research Board (SERB) IPA/2020/000405 India Wellcome Trust IA/S/20/1/504916 United Kingdom Science and Engineering Research Board (SERB) CRG/2022/002646 India Structure of beta-arrestin1 in complex with mouse C5aR1pp Banerjee R Yadav R Yadav MK Ganguly M Mishra S Dalal A Gati C Shukla AK GPCR, G protein, SIGNALING PROTEIN, beta-arrestin Mishra S Yadav MK Dalal A Ganguly M Yadav R Sawada K Tiwari D Roy N Banerjee N Fung JN Marallag J Cui CS Li XX Lee JD Dsouza CA Saha S Sarma P Rawat G Zhu H Khant HA Clark RJ Sano FK Banerjee R Woodruff TM Nureki O Gati C Shukla AK Molecular fingerprints of a convergent mechanism orchestrating diverse ligand recognition and species-specific pharmacology at the complement anaphylatoxin receptors. Biorxiv US 2025 40501890 doi:10.1101/2025.05.26.656101 2692-8205 9kyu FULLOVERLAP EMDB EMD-62649 associated EM volume
Structure of beta-arrestin1 in complex with mouse C5aR1pp
 beta-arrestin1 in complex with mouse C5aR1pp beta-arrestin1 in complex with mouse C5aR1pp 0 1 2 3 4 Beta-arrestin-1 1 1 Rattus norvegicus Fab30 Heavy Chain and Light chain 1 3 4 Mus musculus mouse C5aR1 phosphopeptide 1 2 Beta-arrestin-1 Rattus norvegicus 0.047088508 2 Escherichia coli LEVO MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLF VANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHK RNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVS YKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEPPHREVPESETPVDTNLIELDTNDDDIVFEDFARQRLKGMK DDKDEEDDGTGSPHLNNR P29066 C5aR1 phosphopeptide Mus musculus 0.002972297 2 LEVO GGGD(SEP)K(TPO)F(TPO)P(SEP)(TPO)(TPO)D(TPO)(SEP)TRKSQAV P30993 Fab30 Heavy Chain Mus musculus 0.025512353999999998 2 Escherichia coli LEVO EISEVQLVESGGGLVQPGGSLRLSCAASGFNVYSSSIHWVRQAPGKGLEWVASISSYYGYTYYADSVKGRFTISADTSKN TAYLQMNSLRAEDTAVYYCARSRQFWYSGLDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPV TVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHHHHHHHH Fab30 Light Chain Mus musculus 0.023435064 2 Escherichia coli LEVO SDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQ PEDFATYYCQQYKYVPVTFGQGTKVEIKRTVAAPSVFIFPPSDSQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNS QESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC singleParticle particle 7.4 ETHANE TFS KRIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 0.8 3.0 GATAN K3 (6k x 4k) COUNTING 53.7 1 cryoSPARC 4.6.2 NONE 8J8Z C2 2.72 FSC 0.143 CUT-OFF cryoSPARC 4.6.2 376105 MAXIMUM LIKELIHOOD cryoSPARC 4.6.2 MAXIMUM LIKELIHOOD cryoSPARC 4.6.2 cryoSPARC 4.6.2 emd_62649.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 384 384 384 0 0 0 384 384 384 388.1856 388.1856 388.1856 90.0 90.0 90.0 X Y Z -0.039292037 1.7869805 0.00051384047 0.013356369 1.0109 1.0109 1.0109 0.0269 AUTHOR FLEXIBLE FIT REAL emd_62649_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 384 384 384 0 0 0 384 384 384 388.1856 388.1856 388.1856 90.0 90.0 90.0 X Y Z -0.44088024 0.86974555 -0.000059330316 0.041778237 1.0109 1.0109 1.0109 AUTHOR emd_62649_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 384 384 384 0 0 0 384 384 384 388.1856 388.1856 388.1856 90.0 90.0 90.0 X Y Z -0.42164204 0.90021735 -0.000057344456 0.041850828 1.0109 1.0109 1.0109 AUTHOR