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    <admin>
        <current_status>
            <date>2025-10-29</date>
            <code>REL</code>
            <processing_site>PDBj</processing_site>
        </current_status>
        <sites>
            <deposition>PDBj</deposition>
            <last_processing>PDBj</last_processing>
        </sites>
        <key_dates>
            <deposition>2024-12-19</deposition>
            <header_release>2025-10-29</header_release>
            <map_release>2025-10-29</map_release>
            <update>2025-10-29</update>
        </key_dates>
        <grant_support>
            <grant_reference>
                <funding_body>Academia Sinica (Taiwan)</funding_body>
                <code>AS-IDR-112-04</code>
                <country>Taiwan</country>
            </grant_reference>
            <grant_reference>
                <funding_body>Academia Sinica (Taiwan)</funding_body>
                <code>AS-CDA-109-L08</code>
                <country>Taiwan</country>
            </grant_reference>
        </grant_support>
        <title>Cryo-EM structure of SARS-CoV-2 S-BQ.1 in complex with Ace2 constituent map 1</title>
        <authors_list>
            <author>Hsu HF</author>
            <author>Wu MH</author>
            <author>Chang YC</author>
            <author>Hsu STD</author>
        </authors_list>
        <keywords>spike protein, VIRAL PROTEIN</keywords>
    </admin>
    <crossreferences>
        <citation_list>
            <primary_citation>
                <journal_citation published="true">
                    <author order="1">Chang YH</author>
                    <author order="2">Hsu MF</author>
                    <author order="3">Chen WN</author>
                    <author order="4">Wu MH</author>
                    <author order="5">Kong WL</author>
                    <author order="6">Lu MJ</author>
                    <author order="7">Huang CH</author>
                    <author order="8">Chang FJ</author>
                    <author order="9">Chang LY</author>
                    <author order="10">Tsai HY</author>
                    <author order="11">Tung CP</author>
                    <author order="12">Yu JH</author>
                    <author order="13">Kuo Y</author>
                    <author order="14">Chou YC</author>
                    <author order="15">Bai LY</author>
                    <author order="16">Chang YC</author>
                    <author order="17">Chen AY</author>
                    <author order="18">Chen CC</author>
                    <author order="19">Chen YH</author>
                    <author order="20">Liao CC</author>
                    <author order="21">Chang CS</author>
                    <author order="22">Liang JJ</author>
                    <author order="23">Lin YL</author>
                    <author order="24">Angata T</author>
                    <author order="25">Hsu SD</author>
                    <author order="26">Lin KI</author>
                    <title>Functional and structural investigation of a broadly neutralizing SARS-CoV-2 antibody.</title>
                    <journal_abbreviation>JCI Insight</journal_abbreviation>
                    <volume>9</volume>
                    <year>2024</year>
                    <external_references type="PUBMED">38775156</external_references>
                    <external_references type="DOI">doi:10.1172/jci.insight.179726</external_references>
                    <external_references type="ISSN">2379-3708</external_references>
                </journal_citation>
            </primary_citation>
        </citation_list>
        <other_db_list>
            <db_reference>
                <db_name>EMDB</db_name>
                <accession_id>EMD-62800</accession_id>
                <content_type>associated EM volume</content_type>
            </db_reference>
        </other_db_list>
    </crossreferences>
    <sample>
        <name>SARS-CoV-2 S-BQ.1 and ACE2 complex</name>
        <supramolecule_list>
            <complex_supramolecule supramolecule_id="1">
                <name>SARS-CoV-2 S-BQ.1 and ACE2 complex</name>
                <parent>0</parent>
                <macromolecule_list>
                    <macromolecule>
                        <macromolecule_id>1</macromolecule_id>
                    </macromolecule>
                </macromolecule_list>
                <natural_source database="NCBI">
                    <organism ncbi="2697049">Severe acute respiratory syndrome coronavirus 2</organism>
                </natural_source>
            </complex_supramolecule>
        </supramolecule_list>
        <macromolecule_list>
            <protein_or_peptide macromolecule_id="1">
                <name>spike glycoprotein</name>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MFVFLVLLPLVSSQCVNLITRTQSYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAISGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLDVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLGRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFDEVFNATRFASVYAWNRKRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSTVGGNYNYRYRLFRKSKLKPFERDISTEIYQAGNKPCNGVAGVNCYFPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEYVNNSYECDIPIGAGICASYQTQTKSHGSASSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLKRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKYFGGFNFSQILPDPSKPSKRSPIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFKGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGPALQIPFPMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTPSALGKLQDVVNHNAQALNTLVKQLSSKFGAISSVLNDILSRLDPPEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQEFGSGGYIPEAPRDGQAYVRKDGEWVLLSTFLKGQDNSADIQHSGRPLESRGPFEQKLISEEDLNMHTGHHHHHH</string>
                </sequence>
            </protein_or_peptide>
        </macromolecule_list>
    </sample>
    <structure_determination_list>
        <structure_determination structure_determination_id="1">
            <method>singleParticle</method>
            <aggregation_state>threeDArray</aggregation_state>
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                    <concentration units="mg/mL">2</concentration>
                    <buffer>
                        <ph>7.4</ph>
                    </buffer>
                </single_particle_preparation>
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            <microscopy_list>
                <single_particle_microscopy microscopy_id="1">
                    <microscope>TFS KRIOS</microscope>
                    <illumination_mode>FLOOD BEAM</illumination_mode>
                    <imaging_mode>BRIGHT FIELD</imaging_mode>
                    <electron_source>FIELD EMISSION GUN</electron_source>
                    <acceleration_voltage units="kV">300</acceleration_voltage>
                    <nominal_defocus_min units="µm">0.8</nominal_defocus_min>
                    <nominal_defocus_max units="µm">2.6</nominal_defocus_max>
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                        <image_recording image_recording_id="1">
                            <film_or_detector_model>GATAN K3 (6k x 4k)</film_or_detector_model>
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                        </image_recording>
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                    <pdb_model>
                        <pdb_id>8DM5</pdb_id>
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                    <resolution_method>FSC 0.143 CUT-OFF</resolution_method>
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                    <type>MAXIMUM LIKELIHOOD</type>
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    <interpretation>
        <modelling_list>
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                <refinement_protocol>RIGID BODY FIT</refinement_protocol>
                <refinement_space>REAL</refinement_space>
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