2025-12-10 REL PDBc INITIAL_RELEASE REPOSITORY PDBj PDBc 2025-01-13 2025-12-10 2025-12-10 2025-12-10 Other government 202403021211192 China National Natural Science Foundation of China (NSFC) 32161133022 China Cryo-EM structure of GPR155 monomer in complex with cholesterol Gao F Zhang X Li D Pu H cholesterol, mTORC1 regulation, GPCR, transceptor, MEMBRANE PROTEIN Li D Zhang X Feng J Xie Y Han P He M Hao L Guo T Bai X Yuan K Sun J Pang X Wu Y Liu Y Gao GF Huang N Xiao H Gao F Structural insight into GPR155-mediated cholesterol sensing and signal transduction. Sci Bull (Beijing) CN 70 3625 3637 2025 41058362 doi:10.1016/j.scib.2025.09.012 2095-9281 9lhq FULLOVERLAP EMDB EMD-63104 associated EM volume
Cry0-EM structure of GPR155 monomer in complex with cholesterol
 GPR155 in complex with cholesterol GPR155 in complex with cholesterol 0 1 Homo sapiens Lysosomal cholesterol signaling protein Homo sapiens 0.101046047 1 Schizosaccharomyces pombe LEVO MNSNLPAENLTIAVNMTKTLPTAVTHGFNSTNDPPSMSITRLFPALLECFGIVLCGYIAGRANVITSTQAKGLGNFVSRF ALPALLFKNMVVLNFSNVDWSFLYSILIAKASVFFIVCVLTLLVASPDSRFSKAGLFPIFATQSNDFALGYPIVEALYQT TYPEYLQYIYLVAPISLMMLNPIGFIFCEIQKWKDTQNASQNKIKIVGLGLLRVLQNPIVFMVFIGIAFNFILDRKVPVY VENFLDGLGNSFSGSALFYLGLTMVGKIKRLKKSAFVVLILLITAKLLVLPLLCREMVELLDKGDSVVNHTSLSNYAFLY GVFPVAPGVAIFATQFNMEVEIITSGMVISTFVSAPIMYVSAWLLTFPTMDPKPLAYAIQNVSFDISIVSLISLIWSLAI LLLSKKYKQLPHMLTTNLLIAQSIVCAGMMIWNFVKEKNFVGQILVFVLLYSSLYSTYLWTGLLAISLFLLKKRERVQIP VGIIIISGWGIPALLVGVLLITGKHNGDSIDSAFFYGKEQMITTAVTLFCSILIAGISLMCMNQTAQAGSYEGFDQSQSH KVVEPGNTAFEESPAPVNEPELFTSSIPETSCCSCSMGNGELHCPSIEPIANTSTSEPVIPSFEKNNHCVSRCNSQSCIL AQEEEQYLQSGDQQLTRHVLLCLLLIIGLFANLSSCLWWLFNQEPGRLYVELQFFCAVFNFGQGFISFGIFGLDKHLIIL PFKRRLEFLWNNKDTAENRDSPVSEEIKMTCQQFIHYHRDLCIRNIVKERRCGAKTSAGTFCGCDLVSWLIEVGLASDRG EAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRFLQKSPEQSPPAINANTLQQERYKEIEHSSPPSHSPKTAAAENLYFQG LWSHPQFEKGGGSGGGSGGSAWSHPQFEK Q7Z3F1 CHOLESTEROL 0.000386654 7 CLR singleParticle particle 3.3 8.0 ETHANE TFS KRIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 -1.0 -2.0 GATAN K3 (6k x 4k) 50.0 1 PHASE FLIPPING AND AMPLITUDE CORRECTION
ab initio 3d by cryoSPARC
 3.46 FSC 0.143 CUT-OFF 645636 MAXIMUM LIKELIHOOD MAXIMUM LIKELIHOOD emd_63104.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 400 400 400 0 0 0 400 400 400 340.0 340.0 340.0 90.0 90.0 90.0 X Y Z -1.5571309 2.2977788 -0.00018385843 0.024147226 0.85 0.85 0.85 0.351 AUTHOR EM map of monomer with CHL emd_63104_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 400 400 400 0 0 0 400 400 400 340.0 340.0 340.0 90.0 90.0 90.0 X Y Z -0.33549666 0.74886763 0.00045331725 0.017890122 0.85 0.85 0.85 AUTHOR Half map A of monomer with CHL emd_63104_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 400 400 400 0 0 0 400 400 400 340.0 340.0 340.0 90.0 90.0 90.0 X Y Z -0.3479042 0.80292875 0.00045781332 0.017875437 0.85 0.85 0.85 AUTHOR Half map A of monomer with CHL