2025-11-26 REL PDBc INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY PDBj PDBc 2025-01-28 2025-11-26 2025-11-26 2025-11-26 National Natural Science Foundation of China (NSFC) China Cryo-EM structure of NTR-bound type III-B CRISPR-Cas effector complex Jin X Duan B Chen Z Zhao B CRISPR-Cas complex, adaptive immunity, RNA degradation, second messenger, IMMUNE SYSTEM/RNA, IMMUNE SYSTEM-RNA complex Duan B Jin X Chen Z Zhao B Mechanisms of SAM-AMP synthesis and degradation in antiviral type III CRISPR signaling. To Be Published 0353 9lq7 FULLOVERLAP EMDB EMD-63295 associated EM volume
Cryo-EM structure of NTR-bound type III-B CRISPR-Cas effector complex
 NTR-bound type III-B CRISPR-Cas effector complex NTR-bound type III-B CRISPR-Cas effector complex 0 1 2 3 4 5 6 7 8 Bacteroides fragilis Cmr1 Bacteroides fragilis 0.05534025 1 Escherichia coli LEVO MNQLTAILKQHTPMIHFQHNESGATLRASEVKPLLDKFILTKLGNGDIREGRLYAKKNNWLIDNEKNYALNYKLSISLQK KSRLEYLITSSTFPLPTERPSNFFTIQNSPYFAQEKCVGINTNSTIILKKSNSDPRKKEAEFKEKNWSQIDKKGLEWQDF TIKIFSLKGDLINKIQTYLPAFFICHNFGTRNNKGFGSFTVEYINNQKNICNVEDTLKENFAFVYKKKIALSRQSTLDFI YIYNQIFSTIKKDYQILKSGYNFRNEYIKSLLFCYFVSKYPNYRWEKRKMKQLIKARGYELKGDHSPISGIRENDNSWND PNPNGYNYAYIRAILGLAEQYEFQLETPYQKAIVKIKSANNCISRYKSPLLFKIINNSIYLVGNEINTEILNKPFQYSYI EQTKNKNMRTGKSEITERTMHINEIEMNYKNRINYHYTPTSFSLIDFMQYAMSYKKNGKNILNYIPLKQ A0A5M5QTL0 Type III-B CRISPR-associated protein Cas10/Cmr2 Bacteroides fragilis 0.06924707799999999
deletioins
1 Escherichia coli LEVO MKYIAITLGPITRTIEMAESTKELWAASYFFSYLAKKIVEPFVKKNRTFQLPLINEEMQKPHCGAGLFPDRYIFKSEPGD LELLKQHSDQVLIEIAGHIASPSLPGTAKDVSQIYHYLKSYIKIYFIERTLESDDPHVVIPACEKYLNIIENQETFPEQE ETMISHQKSDFLKFLITNVNGKIYRKDKNSIPRFTGSFLTRDAFGDMNGERLFESILEISASELNINIQQKALEVITANE KNKGEKYSDQIWDAEEIILNDNKAQLRPYHKYIAIIKSDGDSMGETIKSMGAYNIPITQLSKALLSFNIESINEIVAYGG KPIFIGGDDLLCFAPVCCNGNNVFNLVEKLSTCFDQCINQHLQQYINACSEAQRPLPSLSFGISITYHKYPMFEALHTTD YLLEMVAKDNLFKYTLSNKNILNENMKRFILKNKLAFSLQKHSGQIYHTAMSKKGKSYVKFNMLLQKYILKNKDMSKTQE SEKFLSSVIQMIRAHAEILQIILQNEDKRTEMLKNYFDNNFNESCHLGYTGLFEDIQTLLCLRYQENIQDYQNRNEIIQQ NTILTSDEKEILIVSPAMDAIHTIFTALQFIHFINYNKDE A0A5C6J4N7 CRISPR-associated protein Cmr3 Bacteroides fragilis 0.049059207
deletions
1 Escherichia coli LEVO MSHHHHHHHHDGKPIPNPLLGLDSTGSDQTENSGENLYFQGANAMNRHYLITLTPMDWFFFGGERTLDDGKSADYISHSN KFPQQSALLGMIRYQLLKQHNLLSQFPYTENKPTEKEIMKTLIGEQSFRMTERKAKSLGLGVIKQISPLMLIECKDDTSS RSIYFPLPLDDGYKVSFNETSNEDKVFYNGIECPIPNVYPASEEQDSGNQKRKFFDHKTYNNYLFWCTQGNNQIKKLLSD EIWISKMQIGITKHVEEGEDNDKSFYKQEFLQLKKSFIYAFYITLSGESELSSDIIQLGGQRSVFRMEVESIEENSDIQE KYQTAAQFLTQSDRLLILSPTYVDNLKELSALCNFMWSDSIVFRNIQTTNASNFYGKPIKSSSKYHFLKPGSVLYFKQGK RKEVEKLLMDYTYLRLSGYNIYI A0A9X9IKM4 Type III-B CRISPR module RAMP protein Cmr4 Bacteroides fragilis 0.031537041 3 Escherichia coli LEVO MTTRMYVINTLSNMHVGSGEVNYGVIANLIQRDSVTNLPNINSSGLKGAIREYFKENEDLVRELFGSAPRDEKTLPGKVR FFEANLLSMPVRSDKVPFLMAISDEVLQELITKMKFFNCEEATQYISHLSTLLDNIKTQAQGTDFAYVFDPLLQGAIIEE VSIRATCPSHIPLQPSLKKLLGDRLVILSHKYFSILSDDNHLPVLSRNNLENGQSANLWYEQVLPRYSRLYFMLMDGNAQ SEYLKKFRDTLCTPSTIIQIGANASIGYGYCQISELSPF A0A9X9NER2 CRISPR type III-B/RAMP module-associated protein Cmr5 Bacteroides fragilis 0.015273492999999999 2 Escherichia coli LEVO MKISKKQIEYAIEALRANNIITNDNQYPKVFKGYISSFGAAVIQSGLIPAIIFFENEDNDANADRHKIIGVLKDIINAMR QQYTVTDATILVSSQIPANYSMAQYIIEHGNTDQLLKEITEAAVAMKLALRMYKSE A0A2M9V7H9 RAMP superfamily protein Bacteroides fragilis 0.035951883 1 Escherichia coli LEVO MPKNYTLQNASNLGWLFYKDYYRQEPNVDFISTQGKESDTTADFFRKTNQRITAYQLNSESPLVAAFNNHFGTPLQLKTI YPGLITGSGLPHQTGSKGEFKLGFQFDYTTGLPYIPGSSIKGTLRSMFPFSLKDKGSTKRILPEYRKERMEYIRDLIIEV TNINEISDTEIQALEYAIFTNSTPSGKTIEFSLEEKDVFYDAFVADSKDGVMLSDDYITPHGENPLKDPKPILFLKIRPD VTINFYFKLCTTHLYKEKVCSSKQIEEIKKQNDFSSSDYKMITAHQKRNLFEKILLCIGIGAKTNIGYGQLKKL A0A2M9V7I0 NTR Bacteroides fragilis 0.015672396
deletions
1 CACAAGGGACGCCACUUCAUGGAAAUAAAUCACUCACGAAUGUCUUAAU crRNA Bacteroides fragilis 0.015671214
deletions
1 AUUAAGACAUUCGUGAGUGAUUUAUUUCCAUGAAGUGGCGUCCCUUGUG ADENOSINE-5'-TRIPHOSPHATE 0.000507181 1 ATP S-ADENOSYLMETHIONINE 0.000398437 1 SAM MANGANESE (II) ION 5.4938e-05 1 MN singleParticle particle 7.5 ETHANE 100 TFS KRIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 1.0 3.0 TFS FALCON 4i (4k x 4k) 50.0 1 PHASE FLIPPING AND AMPLITUDE CORRECTION 2.81 FSC 0.143 CUT-OFF 67694 PROJECTION MATCHING PROJECTION MATCHING emd_63295.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 360 360 360 0 0 0 360 360 360 335.52 335.52 335.52 90.0 90.0 90.0 X Y Z -0.1616595 37.045499999999997 -0.005051995 0.59667796 0.932 0.932 0.932 0.1 AUTHOR emd_63295_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 360 360 360 0 0 0 360 360 360 335.52 335.52 335.52 90.0 90.0 90.0 X Y Z -0.84505254 1.9898295 0.0016684539 0.08983272 0.932 0.932 0.932 AUTHOR emd_63295_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 360 360 360 0 0 0 360 360 360 335.52 335.52 335.52 90.0 90.0 90.0 X Y Z -0.8463133 1.9919925 0.0016796798 0.08974179 0.932 0.932 0.932 AUTHOR