2026-03-04 REL PDBc INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY PDBj PDBc 2025-02-24 2026-03-04 2026-03-04 2026-03-04 National Natural Science Foundation of China (NSFC) 82121005 China Cryo-EM structure of Bombesin receptor type-3 bound to oridonin Li C Xu Y Yin W Xu H oridonin, GPCR, BRS3, SIGNALING PROTEIN/IMMUNE SYSTEM, SIGNALING PROTEIN-IMMUNE SYSTEM complex Li C Xu Y Yin W Xu H Cryo-EM structure of Bombesin receptor type-3 bound to oridonin To Be Published 0353 9m0j FULLOVERLAP EMDB EMD-63545 associated EM volume
Cryo-EM strucutre of Bombesin receptor type-3 bound to oridonin
 Cryo-EM structure of Bombesin receptor subtype-3 bound to oridonin Cryo-EM structure of Bombesin receptor subtype-3 bound to oridonin 0 1 2 3 4 5 Homo sapiens 0.16 Guanine nucleotide-binding protein G(q) subunit alpha-1 Homo sapiens 0.041724383 1 Trichoplusia ni LEVO MGCTLSAEDKAAVERSKMIEKQLQKDKQVYRRTLRLLLLGADNSGKSTIVKQMRIYHVNGYSEEECKQYKAVVYSNTIQS IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD RIAQPNYIPTQQDVLRTRVKTSGIFETKFQVDKVNFHMFDVGAQRDERRKWIQCFNDVTAIIFVVDSSDYNRLQEALNDF KSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRKEFVDISTASG DGRHICYPHFTCSVDTENARRIFNDCKDIILQMNLREYNLV Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Homo sapiens 0.037784301 1 Trichoplusia ni LEVO GSLLQSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQD GKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFP NGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVS CLGVTDDGMAVATGSWDSFLKIWN P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Homo sapiens 0.007861143 1 Trichoplusia ni LEVO MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL P59768 Nanobody-35 synthetic construct 0.013885439 1 Escherichia coli BL21(DE3) LEVO QVQLQESGGGLVQPGGSLRLSCAASGFTFSNYKMNWVRQAPGKGLEWVSDISQSGASISYTGSVKGRFTISRDNAKNTLY LQMNSLKPEDTAVYYCARCPAPFTRDCFDVTSTTYAYRGQGTQVTVSS Bombesin receptor subtype-3 Homo sapiens 0.044452667999999994 1 Trichoplusia ni LEVO MAQRQPHSPNQTLISITNDTESSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKSMQT VPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNA ILKTCVKAGCVWIVSMIFALPEAIFSNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFYIIPLSIISVYYSLI ARTLYKSTLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQTYVDPSAMHFIFTIFSRVLAF SNSCVNPFALYWLSKSFQKHFKAQLFCCKAERPEPPVADTSLTTLAVMGTVPGTGSIQMSEISVTSFTGCSVKQAEDRF P32247 (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R,16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one 0.000366449 1 ODN singleParticle particle 7.5 ETHANE FEI TALOS ARCTICA FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 1.2 5.0 GATAN K3 (6k x 4k) 50.0 1 NONE 8H0Q 2.9 FSC 0.143 CUT-OFF cryoSPARC 179257 ANGULAR RECONSTITUTION ANGULAR RECONSTITUTION emd_63545.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 256 256 256 0 0 0 256 256 256 186.88 186.88 186.88 90.0 90.0 90.0 X Y Z -2.2276864 3.2097082 0.0051668817 0.086513154 0.73 0.73 0.73 0.219 AUTHOR emd_63545_msk_1.map emd_63545_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 256 256 256 0 0 0 256 256 256 186.88 186.88 186.88 90.0 90.0 90.0 X Y Z -0.49945873 1.0527283 0.0028499076 0.04769504 0.73 0.73 0.73 AUTHOR emd_63545_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 256 256 256 0 0 0 256 256 256 186.88 186.88 186.88 90.0 90.0 90.0 X Y Z -0.54418075 1.0089283 0.0028175307 0.047347475 0.73 0.73 0.73 AUTHOR