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        <grant_support>
            <grant_reference>
                <funding_body>National Natural Science Foundation of China (NSFC)</funding_body>
                <code>92469108</code>
                <country>China</country>
            </grant_reference>
        </grant_support>
        <title>Cryo-EM structure of SARS-CoV-2 KP.2 spike RBD in complex with ACE2</title>
        <authors_list>
            <author>Jin XH</author>
            <author>Sun L</author>
        </authors_list>
        <keywords>Spike and ACE2 complex, Viral protein/Hydrolase, VIRAL PROTEIN-HYDROLASE complex</keywords>
    </admin>
    <crossreferences>
        <citation_list>
            <primary_citation>
                <journal_citation published="true">
                    <author order="1">Shi J</author>
                    <author ORCID="0000-0002-0347-9104" order="2">Zhao X</author>
                    <author order="3">Jin X</author>
                    <author order="4">Li J</author>
                    <author order="5">Liu Y</author>
                    <author order="6">Liu H</author>
                    <author order="7">Hu YF</author>
                    <author order="8">Chen Z</author>
                    <author order="9">Xiao Y</author>
                    <author order="10">Wang L</author>
                    <author order="11">Wang Y</author>
                    <author order="12">He Y</author>
                    <author order="13">Chai Y</author>
                    <author ORCID="0000-0002-6677-9454" order="14">Hu B</author>
                    <author ORCID="0000-0001-8078-4113" order="15">Shuai H</author>
                    <author order="16">Wang Y</author>
                    <author order="17">Li X</author>
                    <author order="18">Jiang S</author>
                    <author order="19">Zhang Y</author>
                    <author order="20">Zhang X</author>
                    <author order="21">Chan WM</author>
                    <author order="22">Chen LL</author>
                    <author order="23">Cai JP</author>
                    <author order="24">Sui B</author>
                    <author order="25">Zhang H</author>
                    <author order="26">Yang D</author>
                    <author order="27">Zhu L</author>
                    <author ORCID="0000-0001-7996-1119" order="28">Yuan S</author>
                    <author ORCID="0000-0002-2948-3873" order="29">Zhou J</author>
                    <author ORCID="0000-0001-7531-2816" order="30">Huang JD</author>
                    <author ORCID="0000-0002-2083-1552" order="31">Yuen KY</author>
                    <author ORCID="0000-0002-1921-5824" order="32">To KK</author>
                    <author ORCID="0000-0001-6336-6657" order="33">Chan JF</author>
                    <author ORCID="0000-0002-8716-2306" order="34">Zhang BZ</author>
                    <author ORCID="0000-0001-6416-1733" order="35">Wang Q</author>
                    <author ORCID="0000-0002-3862-317X" order="36">He M</author>
                    <author ORCID="0000-0001-8741-0202" order="37">Sun L</author>
                    <author ORCID="0000-0003-2454-7652" order="38">Wang P</author>
                    <author ORCID="0000-0003-2855-9837" order="39">Chu H</author>
                    <title>Pathogenicity, virological features, and immune evasion of SARS-CoV-2 JN.1-derived variants including JN.1.7, KP.2, KP.3, and KP.3.1.1.</title>
                    <journal_abbreviation>Nat Commun</journal_abbreviation>
                    <country>UK</country>
                    <volume>16</volume>
                    <first_page>11002</first_page>
                    <last_page>11002</last_page>
                    <year>2025</year>
                    <external_references type="PUBMED">41381428</external_references>
                    <external_references type="DOI">doi:10.1038/s41467-025-66018-x</external_references>
                    <external_references type="ISSN">2041-1723</external_references>
                </journal_citation>
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                <db_name>EMDB</db_name>
                <accession_id>EMD-64077</accession_id>
                <content_type>associated EM volume</content_type>
                <details>Cryo-EM structure of SARS-CoV-2 KP.2 spike RBD in complex with ACE2</details>
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        <name>KP.2 RBD in complex with ACE2</name>
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            <complex_supramolecule supramolecule_id="1">
                <name>KP.2 RBD in complex with ACE2</name>
                <parent>0</parent>
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                    <macromolecule>
                        <macromolecule_id>2</macromolecule_id>
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                <natural_source database="NCBI">
                    <organism ncbi="2697049">Severe acute respiratory syndrome coronavirus 2</organism>
                </natural_source>
            </complex_supramolecule>
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                <name>Spike protein S1</name>
                <natural_source database="NCBI">
                    <organism ncbi="2697049">Severe acute respiratory syndrome coronavirus 2</organism>
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                <number_of_copies>1</number_of_copies>
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GQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKHSGNYDYWYRSLRKSKLKPFERDISTEIYQAGNKPCKGKGPNCYFPLQ
SYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPK</string>
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                </molecular_weight>
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QMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNE
RLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHL
HAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGL
PNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGF
HEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEM
KREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRL
GKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADLEVLFQGPHHHHHHHH</string>
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