2025-12-03 REL PDBc INITIAL_RELEASE REPOSITORY DATABASE_REFERENCES citation citation_author em_admin _citation.journal_volume _citation.page_first _citation.page_last _citation.pdbx_database_id_PubMed _citation.title _citation_author.identifier_ORCID _em_admin.last_update PDBj PDBc 2025-05-15 2025-11-19 2025-11-19 2025-12-03 National Natural Science Foundation of China (NSFC) 82121005 China National Natural Science Foundation of China (NSFC) 32401012 China Composite map of the G protein-coupled receptor 1 (GPR1) bound to chemerin and beta-arrestin 2 Cai H Lin X Zhao L He M Yu J Zhang B Ma Y Xie C Shui W Zhao Q Zhu Y Wu B G protein-coupled receptor 1, chemerin, beta-arrestin 2, signaling protein, MEMBRANE PROTEIN/IMMUNE SYSTEM, MEMBRANE PROTEIN-IMMUNE SYSTEM complex Cai H Lin X Zhao L He M Yu J Zhang B Ma Y Chang X Tang Y Luo T Jiang J Ma M Song W Ma L Chu X Yi C Chen K Han S Xie C Shui W Zhao Q Zhu Y Wu B Noncanonical agonist-dependent and -independent arrestin recruitment of GPR1. Science US 390 eadt8794 eadt8794 2025 41264711 doi:10.1126/science.adt8794 1095-9203 0038 SCIEAS EMD-64615 focused EM volume
Cryo-EM structure of the G protein-coupled receptor 1 (GPR1) bound to chemerin and beta-arrestin 2 (focused refinement in chemerin and GPR1)
 EMD-64616 focused EM volume
Cryo-EM structure of the G protein-coupled receptor 1 (GPR1) bound to chemerin and beta-arrestin 2 (focused refinement in beta-arrestin 2)
 EMD-64617 consensus EM volume
Cryo-EM structure of the G protein-coupled receptor 1 (GPR1) bound to chemerin and beta-arrestin 2 (consensus refinement)
 9uym FULLOVERLAP EMDB EMD-64615 focused EM volume
Cryo-EM structure of the G protein-coupled receptor 1 (GPR1) bound to chemerin and beta-arrestin 2 (focused refinement in chemerin and GPR1)
 EMDB EMD-64616 focused EM volume
Cryo-EM structure of the G protein-coupled receptor 1 (GPR1) bound to chemerin and beta-arrestin 2 (focused refinement in beta-arrestin 2)
 EMDB EMD-64617 consensus EM volume
Cryo-EM structure of the G protein-coupled receptor 1 (GPR1) bound to chemerin and beta-arrestin 2 (consensus refinement)
 EMDB EMD-64618 associated EM volume
Composite map of the G protein-coupled receptor 1 (GPR1) bound to chemerin and beta-arrestin 2
 G protein-coupled receptor 1 in complex with chemerin and beta-arrestin2 G protein-coupled receptor 1 in complex with chemerin and beta-arrestin2 0 1 2 3 4 5 Homo sapiens Retinoic acid receptor responder protein 2 Homo sapiens 0.017720475 1 Spodoptera frugiperda LEVO MKTIIALSYIFCLVFAELTEAQRRGLQVALEEFHKHPPVQWAFQETSVESAVDTPFPAGIFVRLEFKLQQTSCRKRDWKK PECKVRPNGRKRKCLACIKLGSEDKVLGRLVHCPIETQVLREAEEHQETQCLRVQRAGEDPHSFYFPGQFAFS Q99969 Nanobody 32 Escherichia phage EcSzw-2 0.013238716 1 Escherichia coli BL21 LEVO QVQLQESGGGLVQAGGSLRLSCVVSGFFFDTVTMAWYRRAPGKHRELVASATAGGTTTYADSVKDRFTISRDNAKNTVYL QMNSLKPEDTAVYYCNTFVRSLSWGQGTQVTVSSHHHHHH Single-chain fragment variable 30 (scFv30) Homo sapiens 0.026157861 1 Spodoptera frugiperda LEVO SDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQ PEDFATYYCQQYKYVPVTFGQGTKVEIKGTTAASGSSGGSSSGAEVQLVESGGGLVQPGGSLRLSCAASGFNVYSSSIHW VRQAPGKGLEWVASISSYYGYTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARSRQFWYSGLDYWGQGTLV TVSSA Beta-arrestin-2,Beta-arrestin-1 Homo sapiens 0.04150848 1 Spodoptera frugiperda LEVO MGEKPGTRVFKKSSPNGKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTVAFRYGREDLDVLGLSFRKDL FIATYQAFPPVPNPPRPPTRLQDRLLRKLGQHAHPFFFTIPQNLPSSVTLQPGPEDTGKALGVDFEIRAFVAKSLEEKSH KRNSVRLVIRKVQFAPEKPGPQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYA DIVLFSTAQYKVPVAQLEQDDQVSPSSTFSKVYTITPLLSDNREKRGLALDGKLKHEDTNLASSTIVKEGANKEVLGILV SYRVKVKLVVSRGGDVSVELPFVLMHPKPKEEPPHREVPENETPVDTNL P32121 P49407 Chemerin-like receptor 2,Vasopressin V2 receptor Homo sapiens 0.04803183999999999 1 Spodoptera frugiperda LEVO MKTIIALSYIFCLVFAGSWSHPQFEKGSGAGASAGSWSHPQFEKGSDYKDDDDKEFLEVLFQGPEDLEETLFEEFENYSY DLDYYSLESDLEEKVQLGVVHWVSLVLYCLAFVLGIPGNAIVIWFTGFKWKKTVTTLWFLNLAIADFIFLLFLPLYISYV AMNFHWPFGIWLCKANSFTAQLNMFASVFFLTVISLDHYIHLIHPVLSHRHRTLKNSLIVIIFIWLLASLIGGPALYFRD TVEFNNHTLCYNNFQKHDPDLTLIRHHVLTWVKFIIGYLFPLLTMSICYLCLIFKVKKRSILISSRHFWTILVVVVAFVV CWTPYHLFSIWELTIHHNSYSHHVMQAGIPLSTGLAFLNSCLNPILYVLISKKFQARFRSSVAEIARGRTPPSLGPQDE (SEP)C(TPO)(TPO)A(SEP)(SEP)(SEP)LAKDTSS P46091 P30518 CHOLESTEROL HEMISUCCINATE 0.000486726 1 Y01 singleParticle particle 7.5 ETHANE TFS KRIOS SPOT SCAN BRIGHT FIELD FIELD EMISSION GUN 300 0.8 1.5 GATAN K3 BIOQUANTUM (6k x 4k) 2.1875 1 NONE 3.5 FSC 0.143 CUT-OFF 123307 MAXIMUM LIKELIHOOD MAXIMUM LIKELIHOOD emd_64618.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 256 256 256 0 0 0 256 256 256 274.176 274.176 274.176 90.0 90.0 90.0 X Y Z -1.1090516 2.396503 0.0091756005 0.043335244 1.071 1.071 1.071 0.19 AUTHOR Cryo-EM structure of the G protein-coupled receptor 1 (GPR1) bound to chemerin and beta-arrestin 2