2026-03-18 REL PDBc INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY PDBj PDBc 2025-07-25 2026-03-18 2026-03-18 2026-03-18 Not funded Cryo-EM structure of SARS-CoV-2 WT spike protein in complex with nAb 1C4 Sun H Jiang Y Li S Zheng Q SARS-CoV-2, Neutralizing antibody, Cryo-EM, Viral protein/Immune system, Viral protein-immune system complex, VIRAL PROTEIN Sun H Jiang Y Lan M Zhou M Yi G Shen J Deng T Liu L Huang Y Li Y Su J Lin Y Chen Z Zhou L Li T Yu H Cheng T Zhang Y Yuan L Li S Gu Y Zhang P Xia N Zheng Q Engineering a multivalent antibody nanoparticle to overcome SARS-CoV-2 Omicron immune evasion. Plos Pathog. US 21 e1013744 e1013744 2025 41359663 doi:10.1371/journal.ppat.1013744 1553-7374 9w14 FULLOVERLAP EMDB EMD-65523 associated EM volume
Cryo-EM structure of SARS-CoV-2 WT spike protein in complex with nAb 1C4
 Cryo-EM structure of SARS-CoV-2 WT spike protein in complex with nAb 1C4 Cryo-EM structure of SARS-CoV-2 WT spike protein in complex with nAb 1C4 0 1 2 3 SARS-CoV-2 spike protein of WT variant 1 1 Severe acute respiratory syndrome coronavirus 2 The fragment of nAb 1C4 1 2 3 Mus musculus Spike protein S1 Severe acute respiratory syndrome coronavirus 2 WT 0.025122336 1 Homo sapiens LEVO RVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYAD SFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGST PCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNF P0DTC2 Light chain of nAb 1C4 Mus musculus 0.011642854 1 LEVO DIVLTQSPATLSVTPGDNVSLSCRASQIISNNLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSGTDFTLSINSVET EDFGMYFCQQSNTWPLTCGSGTKLELN Heavy chain of nAb 1C4 Mus musculus 0.013384899999999998 1 LEVO QIQLVQSGPELKKPGETVKISCKASGYTFTDYGLNWVKQAPGKGLKWMGWINTYSGEPTYNDEFRGRFAFSLETSTITAY LKINNLKNEDTATYFCARGGNWDWYFDVWGAGTTVTVSS singleParticle particle 7.4 ETHANE FEI TECNAI F30 FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 1.0 1.5 GATAN K3 (6k x 4k) 48.0 1 PHASE FLIPPING AND AMPLITUDE CORRECTION 2.33 FSC 0.143 CUT-OFF cryoSPARC 91916 MAXIMUM LIKELIHOOD MAXIMUM LIKELIHOOD emd_65523.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 648 648 648 0 0 0 648 648 648 421.19998 421.19998 421.19998 90.0 90.0 90.0 X Y Z -0.18047258 0.5195581 -0.00049424823 0.008958683 0.65 0.65 0.65 0.04 AUTHOR emd_65523_additional_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 648 648 648 0 0 0 648 648 648 421.19998 421.19998 421.19998 90.0 90.0 90.0 X Y Z -0.047174864 1.3753387 0.00013245447 0.00399927 0.65 0.65 0.65 AUTHOR emd_65523_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 648 648 648 0 0 0 648 648 648 421.19998 421.19998 421.19998 90.0 90.0 90.0 X Y Z -0.47690263 0.69708264 0.00009880469 0.03667663 0.65 0.65 0.65 AUTHOR emd_65523_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 648 648 648 0 0 0 648 648 648 421.19998 421.19998 421.19998 90.0 90.0 90.0 X Y Z -0.43385977 0.7317433 0.00009765281 0.037049316 0.65 0.65 0.65 AUTHOR