2025-08-27 REL RCSB RCSB RCSB 2025-04-25 2025-08-27 2025-08-27 2025-08-27 National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) UM1 AI144462 United States BG505 MD39.3-CC5 SOSIP in complex with C3V5 epitope polyclonal Fabs isolated from HVTN302 human trial after dose 3 of mRNA-gp151-CD4KO immunization Lee W-H Ozorowski G Ward AB HVTN 302, clinical trial, HIV-1, Env, vaccine-elicited, EMPEM, VIRAL PROTEIN Parks KR Moodie Z Allen MA Yen C Furch BD MacPhee KJ Ozorowski G Heptinstall J Hahn WO Zheng Z Lu H Grant S Domin E Duff MO Seese A Marini-Macouzet C Ballweber-Fleming L Lee WH Cottrell CA Liguori A Georgeson E Alavi N Kubitz M Phelps N Seaton KE Cohen KW Anderson MA Mondal K Laufer DS Kublin JG Ward AB Hyrien O De Rosa SC Himansu S Leav B Reuter C Tomaras GD Montefiori D Walsh SR Frank I Sobieszczyk ME Goepfert PA Stephenson KE Baden LR Van Tieu H Keefer MC Clark J Riddler SA Schief WR McElrath MJ Vaccination with mRNA-encoded membrane-anchored HIV envelope trimers elicited tier 2 neutralizing antibodies in a phase 1 clinical trial. Sci Transl Med US 17 eady6831 eady6831 2025 40737434 doi:10.1126/scitranslmed.ady6831 1946-6242 EMDB EMD-70345 associated EM volume BG505 MD39.3-CC5 SOSIP in complex with C3V5 epitope polyclonal Fabs isolated from HVTN302 human trial after dose 3 of mRNA-gp151-CD4KO immunization BG505 MD39.3-CC5 SOSIP in complex with C3V5 epitope polyclonal Fabs isolated from HVTN302 human trial after dose 3 of mRNA-gp151-CD4KO immunization 0 Human immunodeficiency virus 1 singleParticle particle 0.03 7.4 NEGATIVE uranyl formate Homemade COPPER 400 CARBON CONTINUOUS TFS GLACIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 200 1.0 2.0 FEI TITAN KRIOS AUTOGRID HOLDER FEI FALCON IV (4k x 4k) 16.0 1 NONE 6V0R
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