2026-03-11 REL RCSB INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY DATABASE_REFERENCES citation citation_author em_admin _citation.country _citation.journal_abbrev _citation.journal_id_CSD _citation.journal_id_ISSN _citation.pdbx_database_id_DOI _citation.pdbx_database_id_PubMed _citation.title _citation.year _citation_author.identifier_ORCID _citation_author.name _em_admin.last_update EXPERIMENTAL_SUMMARY citation citation_author em_admin _citation.country _citation.journal_abbrev _citation.journal_id_CSD _citation.journal_id_ISSN _citation.pdbx_database_id_DOI _citation.pdbx_database_id_PubMed _citation.title _citation.year _citation_author.identifier_ORCID _citation_author.name _em_admin.last_update RCSB RCSB 2025-06-04 2026-02-25 2026-02-25 2026-03-11 National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) United States Cryo-EM structure of chicken ROS1 in apo-state. Cryo-EM refinement is focused on the "head" region of chicken ROS1. Bai XC Zhang XW ROS1, STRUCTURAL PROTEIN An W Zhang X Bai XC Structural insights into the activation of the chicken ROS1 receptor by the NEL/NICOL ligand complex. Nat Commun UK 2026 41735298 doi:10.1038/s41467-026-69942-8 2041-1723 9oyz FULLOVERLAP EMDB EMD-71042 associated EM volume
Cryo-EM structure of chicken ROS1 in apo-state. Cryo-EM refinement is focused on the "head" region of chicken ROS1.
 Chicken ROS1 receptor Chicken ROS1 receptor 0 1 Gallus gallus Tyrosine-protein kinase receptor Gallus gallus 0.26117479699999996 1 Homo sapiens LEVO MRNACLLLNRLGAFYFIWISAAYCSFSKNCQDLCTSNLEGELGIANLCNVSDINVACTQGCQFWNATEQVNCPLKCNKTY TRECETVSCKFGCSRAEDAYGVEAQNCLNKPGAPFASSIGSHNITLGWKPANISEVKYIIQWKFHQLPGDWRYTEVVSET SYTVKDLQAFTEYEFRVVWIITSQLQLHSPPSPSYRTHASGVPTTAPIIKDIQSSSPNTVEVSWFPPLFPNGLIVGYNLV LTSENHELLRASRGHSFQFYSTFPNSTYRFSIVAVNEAGAGPPAEANITTPESKVKEKAKWLFLSRNQSLRKRYMEHFLE AAHCLQNGIIHHNITGISVNVYQQVVYFSEGNSIWVKGVVDMSDVSDLTLFYTGWGNITSISVDWLYQRMYFVMNEKIHV CQLENCTAAEDITPPYVTSPRKIVADPYNGYIFCLLEDGIYRANLPLFPDTASAASLVVKSHTLRDFMINFQSKRLIFFN KTEQAFVSGFLDGSEFHTLRAHVPLDDMESFVYEDNIFTVTDGRAVFHEEISQVGSSSFNEYVVDCSLEYPEYFGFGNLL FYAASTQPYPLPTLPRLVTVLFGSDQAVISWSPPEYTIGTSRSAWQNWTYDVKVSSQSTFEEEWVVSNITDTRFAVKNLV SFTEYEMSVRAVSPAGEGPWSEPFRGMTFEEAEEEPYILAVGAEGLWKQRLDSYGPGEFLYPHIRNISDLDWYNDTLYWS NSMGKVQTWSMNKKEGTTENSYVPDIKNARMLAFDWLGQCLYWAGKANTIYRKSLLGDHMDVVAHVVYVVKDLAVDSVNG YLYWATTYTVESARLNGEEYLILQEHLQFSGKQVVGLALDLTSGFLYWLVQDGLCLNLYRISICKESCGNIMVTEISAWS VSEVSQNALQYYSGRLFWINRLKFITTQELNQSISIPFSEPAEFAAFTLVHTSLKPLPGNFSFTPKVIPSSVPESSFKIK GNSSSFHIIWNASTDVQWGTVFYCVGSNALQMRTLESERCLHPHDLTVPSYKVDWLEPFTLFDFSVTPYTYWGKAPTTSV YLRAPEGVPSAPANPRIYVLHSNTHEGEEKVLVELRWDKPERDNGVLTQFRVYYQLLYESGAADTLMEWNVSDVKPTALL FSIRDVHPRLTVRFQVQAFTSVGPGPMSDVAQRNSSDIFPVPTLITFSSNKLFLTDIDSNHTIWEVLTNRNIKDICYTAD DDKVYYILEDSLFLLNVQSTSESQLFEDVFLRNVTAITVDWIARHLFVAMKTSWNETQVFFIDLELKTKSLKALNIQLGK RNSTISSLLSYPFLSRLYWIEELDYGSRMFYYDILNNTMYHILGYESVEEKMRNYCNCNVAEAELGRPISIDVTDIKKPQ LLFIRGRDEIWASDVDGCHCWRITKIPSFQGTKIGSLTVDKQFIYWTIEKKEYTEICLADKESTRHSLQRKANHELKILA YSSAMQSYPDKKCLTPLLDTEKPTILDTTNTSFTLSLPSVTTQQLCPSISQPTPTYLVFFREITSNHENSTYHFSTLLQK TLEIQEPIAVINNLKPFSSYAIQVAVKNYYSNQNQLAVGRETISTTLYGVPEGVDSIKTVVLSDTTINISWSEPLEPNGP LESIRYQISVNLLSLFPEAPLRKSEFPNGTLSWSVSDLQSGTNNLFKVLAFHPNENWFSESVPVIAKTFETPLSPSNIIP RNTSFQLEWRAPLHINGTSFWFELRKWQTRSDWFSPASTTCTVGPVYTCNLTGTLPSANYLVRATVVYVTGMKSTSSPTS FKTTAGVPSKPGTPKRAEDSKNSVQWEKAEDNGSNLTYYILESRKQSGNTNKVKSLWVVVYNGSCDSICTWKAENLEGTF QFRAAAANMLGLGEYSDTSKDIVLAKDTVTSPDITAIVAVIGAVVLGLTIIILFGFVWHQRWKSRKPASTGQIVLVKEDK ELAQLRGMAETVGLANACYAVSTLPSQAEIESLPAFPRDKLNLHKLLGSGAFGEVYEGTALDILADGSGESRVAVKTLKR GATDQEKSEFLKEAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSYLRGARKQKFQSPLLTLTDLLDICLDIC KGCVYLEKMRFIHRDLAARNCLVSEKQYGSCSRVVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLIDGVFTNHSD VWAFGVLVWETLTLGQQPYPGLSNIEVLHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQEIRHSPL CFSYFLGDKESVAGFINQAFEDIDVPPADSDSILSTTLMEARDQEGLNYLVVVKESNQDQGSISSAELTSV F1NQL9 2.7.10.1 2-acetamido-2-deoxy-beta-D-glucopyranose 0.000221208 13 NAG singleParticle particle 8 7.5 Quantifoil R1.2/1.3 GOLD 300 GLOW DISCHARGE ETHANE TFS KRIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 1.2 2.2 FEI TITAN KRIOS AUTOGRID HOLDER GIF Bioquantum 20 GATAN K3 BIOQUANTUM (6k x 4k) 60.0 1 Gctf PHASE FLIPPING AND AMPLITUDE CORRECTION
Made by RELION
 C1 2.9 FSC 0.143 CUT-OFF RELION 255602 PROJECTION MATCHING RELION PROJECTION MATCHING RELION RELION emd_71042.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 350 350 350 0 0 0 350 350 350 412.99997 412.99997 412.99997 90.0 90.0 90.0 X Y Z -0.035706427 0.08138484 0.000028429798 0.0010938323 1.18 1.18 1.18 0.01 AUTHOR Cryo-EM structure of chicken ROS1 in apo-state. Cryo-EM refinement is focused on the "head" region of chicken ROS1. AB INITIO MODEL emd_71042_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 350 350 350 0 0 0 350 350 350 412.99997 412.99997 412.99997 90.0 90.0 90.0 X Y Z -0.023734469 0.0663637 0.000054404984 0.0012054571 1.18 1.18 1.18 AUTHOR Cryo-EM structure of chicken ROS1 in apo-state. Cryo-EM refinement is focused on the "head" region of chicken ROS1, half map 1. emd_71042_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 350 350 350 0 0 0 350 350 350 412.99997 412.99997 412.99997 90.0 90.0 90.0 X Y Z -0.024315452 0.066729575 0.0000538832 0.0012054708 1.18 1.18 1.18 AUTHOR Cryo-EM structure of chicken ROS1 in apo-state. Cryo-EM refinement is focused on the "head" region of chicken ROS1, half map 2.