2026-01-28 REL RCSB INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY DATABASE_REFERENCES citation citation_author em_admin _citation.journal_volume _citation.page_first _citation.page_last _citation_author.identifier_ORCID _em_admin.last_update EXPERIMENTAL_SUMMARY citation citation_author em_admin _citation.journal_volume _citation.page_first _citation.page_last _citation_author.identifier_ORCID _em_admin.last_update RCSB RCSB 2025-06-10 2025-12-24 2025-12-24 2026-01-28 Not funded United States A2AR-BRIL + ZM241385 + PGD2 Rao P Rathinaswamy M Chan M Paredes AG Patel C Wranik BJ Powell J Eaton D Hicks KJ Mafi A Hao Q MEMBRANE PROTEIN Rao P Rathinaswamy M Chan M Paredes AG Patel C Wranik BJ Powell J Eaton D Rutter J Hicks KG Mafi A Hao Q Systematic metabolite screening identifies functional regulators of the adenosine A2A receptor. Commun Chem UK 9 19 19 2025 41366530 doi:10.1038/s42004-025-01825-3 2399-3669 9p1s FULLOVERLAP EMDB EMD-71130 associated EM volume
A2AR-BRIL in complex with ZM241385 and PGD2
 A2AR-BRIL + ZM241385 + PGD2 A2AR-BRIL + ZM241385 + PGD2 0 1 Homo sapiens Adenosine receptor A2a,Soluble cytochrome b562 Homo sapiens 0.047803667999999994 1 Spodoptera frugiperda LEVO DYKDDDDKMPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFCA ACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKEG KAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLKADLEDNWETLNDNLKVIEKADNA AQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQ KYLARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQ TFRKIIRSHVLRQQEPFKAAHHHHHHHHHH P29274 P0ABE7 P29274 Lauryl Maltose Neopentyl Glycol 0.001005188 1 LMN 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol 0.000337336 1 ZMA singleParticle particle 7.5 ETHANE TFS KRIOS OTHER BRIGHT FIELD FIELD EMISSION GUN 300 1.0 2.0 FEI FALCON IV (4k x 4k) 50.0 1 PHASE FLIPPING AND AMPLITUDE CORRECTION 6GDG 3.34 FSC 0.143 CUT-OFF RELION 315882 MAXIMUM LIKELIHOOD MAXIMUM LIKELIHOOD emd_71130.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 256 256 256 0 0 0 256 256 256 206.848 206.848 206.848 90.0 90.0 90.0 X Y Z -0.15898992 0.24603462 0.0001779974 0.003491011 0.808 0.808 0.808 0.0068 AUTHOR emd_71130_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 256 256 256 0 0 0 256 256 256 206.848 206.848 206.848 90.0 90.0 90.0 X Y Z -0.011662762 0.028250294 0.000074181815 0.0010210609 0.808 0.808 0.808 AUTHOR emd_71130_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 256 256 256 0 0 0 256 256 256 206.848 206.848 206.848 90.0 90.0 90.0 X Y Z -0.011335049 0.029275287 0.00007358858 0.0010210426 0.808 0.808 0.808 AUTHOR