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    <admin>
        <current_status>
            <date>2026-02-18</date>
            <code>REL</code>
            <processing_site>RCSB</processing_site>
        </current_status>
        <revision_history>
            <revision version="1.0" date="2026-02-18">
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                        <revision_type>INITIAL_RELEASE</revision_type>
                        <provider>REPOSITORY</provider>
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                        <revision_type>INITIAL_RELEASE</revision_type>
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                        <revision_type>INITIAL_RELEASE</revision_type>
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                        <revision_type>INITIAL_RELEASE</revision_type>
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        <sites>
            <deposition>RCSB</deposition>
            <last_processing>RCSB</last_processing>
        </sites>
        <key_dates>
            <deposition>2025-06-28</deposition>
            <header_release>2026-02-18</header_release>
            <map_release>2026-02-18</map_release>
            <update>2026-02-18</update>
        </key_dates>
        <grant_support>
            <grant_reference>
                <funding_body>National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Disease (NIH/NIDDK)</funding_body>
                <code>DK075037</code>
                <country>United States</country>
            </grant_reference>
        </grant_support>
        <title>NER dual incision complex - DuIS local Bot map</title>
        <authors_list>
            <author ORCID="0009-0002-3070-0887">Li CL</author>
            <author ORCID="0000-0002-3591-2195">Yang W</author>
        </authors_list>
        <keywords>NER, XPA, XPG, XPF, DNA BINDING PROTEIN</keywords>
    </admin>
    <crossreferences>
        <citation_list>
            <primary_citation>
                <journal_citation published="false">
                    <author ORCID="0009-0002-3070-0887" order="1">Li CL</author>
                    <author ORCID="0000-0001-7518-9803" order="2">Kim J</author>
                    <author ORCID="0009-0002-3070-0887" order="3">Yang W</author>
                    <title>Nucleotide Excision Repair Uncovered by Pre-incision Complex Structures</title>
                    <journal_abbreviation>To Be Published</journal_abbreviation>
                    <external_references type="CSD">0353</external_references>
                </journal_citation>
            </primary_citation>
        </citation_list>
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                <db_name>EMDB</db_name>
                <accession_id>EMD-71506</accession_id>
                <content_type>associated EM volume</content_type>
            </db_reference>
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    </crossreferences>
    <sample>
        <name>NER dual incision complex</name>
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            <complex_supramolecule supramolecule_id="1">
                <name>NER dual incision complex</name>
                <parent>0</parent>
                <macromolecule_list>
                    <macromolecule>
                        <macromolecule_id>1</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>2</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>3</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>4</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>5</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>6</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>7</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>8</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>9</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>10</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>11</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>12</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>13</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>14</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>15</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>16</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>17</macromolecule_id>
                    </macromolecule>
                </macromolecule_list>
                <natural_source database="NCBI">
                    <organism ncbi="9606">Homo sapiens</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.8</theoretical>
                </molecular_weight>
            </complex_supramolecule>
        </supramolecule_list>
    </sample>
    <structure_determination_list>
        <structure_determination structure_determination_id="1">
            <method>singleParticle</method>
            <aggregation_state>particle</aggregation_state>
            <specimen_preparation_list>
                <single_particle_preparation preparation_id="1">
                    <concentration units="mg/mL">0.4</concentration>
                    <buffer>
                        <ph>8.0</ph>
                        <component>
                            <concentration units="mM">100.0</concentration>
                            <formula>KOAc</formula>
                            <name>potassium acetate</name>
                        </component>
                        <component>
                            <concentration units="mM">25.0</concentration>
                            <formula>Tris</formula>
                            <name>2-Amino-2-(hydroxymethyl)propane-1,3-diol</name>
                        </component>
                        <component>
                            <concentration units="mM">2.0</concentration>
                            <formula>CaCl2</formula>
                            <name>calcium chloride</name>
                        </component>
                        <component>
                            <concentration units="mM">2.0</concentration>
                            <formula>TCEP</formula>
                            <name>(Tris(2-carboxyethyl)phospine)</name>
                        </component>
                        <component>
                            <concentration units="%">1.0</concentration>
                            <formula>Glycerol</formula>
                            <name>glycerol</name>
                        </component>
                        <component>
                            <concentration units="%">0.05</concentration>
                            <formula>C14H28O6</formula>
                            <name>Octyl glucoside</name>
                        </component>
                    </buffer>
                    <grid>
                        <model>Quantifoil R1.2/1.3</model>
                        <material>COPPER</material>
                        <mesh>300</mesh>
                        <pretreatment>
                            <type>GLOW DISCHARGE</type>
                            <time units="s">60</time>
                            <atmosphere>AIR</atmosphere>
                        </pretreatment>
                    </grid>
                    <vitrification>
                        <cryogen_name>ETHANE</cryogen_name>
                        <chamber_humidity units="percentage">100</chamber_humidity>
                        <chamber_temperature units="K">277.15</chamber_temperature>
                        <instrument>FEI VITROBOT MARK IV</instrument>
                    </vitrification>
                </single_particle_preparation>
            </specimen_preparation_list>
            <microscopy_list>
                <single_particle_microscopy microscopy_id="1">
                    <microscope>TFS KRIOS</microscope>
                    <illumination_mode>FLOOD BEAM</illumination_mode>
                    <imaging_mode>BRIGHT FIELD</imaging_mode>
                    <electron_source>FIELD EMISSION GUN</electron_source>
                    <acceleration_voltage units="kV">300</acceleration_voltage>
                    <c2_aperture_diameter units="µm">70.0</c2_aperture_diameter>
                    <nominal_cs units="mm">2.7</nominal_cs>
                    <nominal_defocus_min units="µm">0.8</nominal_defocus_min>
                    <nominal_defocus_max units="µm">2.4</nominal_defocus_max>
                    <nominal_magnification>105000.0</nominal_magnification>
                    <specimen_holder_model>FEI TITAN KRIOS AUTOGRID HOLDER</specimen_holder_model>
                    <cooling_holder_cryogen>NITROGEN</cooling_holder_cryogen>
                    <alignment_procedure>
                        <coma_free/>
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                        <image_recording image_recording_id="1">
                            <film_or_detector_model>GATAN K3 (6k x 4k)</film_or_detector_model>
                            <number_grids_imaged>6</number_grids_imaged>
                            <number_real_images>52926</number_real_images>
                            <average_exposure_time units="s">3.0</average_exposure_time>
                            <average_electron_dose_per_image units="e/Å^2">52.5</average_electron_dose_per_image>
                        </image_recording>
                    </image_recording_list>
                </single_particle_microscopy>
            </microscopy_list>
            <singleparticle_processing image_processing_id="1">
                <image_recording_id>1</image_recording_id>
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                    <software_list>
                        <software>
                            <name>Gctf</name>
                        </software>
                    </software_list>
                    <type>PHASE FLIPPING AND AMPLITUDE CORRECTION</type>
                </ctf_correction>
                <startup_model type_of_model="NONE"/>
                <final_reconstruction>
                    <number_classes_used>1</number_classes_used>
                    <applied_symmetry>
                        <point_group>C1</point_group>
                    </applied_symmetry>
                    <algorithm>FOURIER SPACE</algorithm>
                    <resolution units="Å" res_type="BY AUTHOR">3.3</resolution>
                    <resolution_method>FSC 0.143 CUT-OFF</resolution_method>
                    <software_list>
                        <software>
                            <name>RELION</name>
                            <version>3.1</version>
                        </software>
                    </software_list>
                    <number_images_used>169165</number_images_used>
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                <initial_angle_assignment>
                    <type>MAXIMUM LIKELIHOOD</type>
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                        <software>
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                            <version>3.1</version>
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                    <type>MAXIMUM LIKELIHOOD</type>
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                        <software>
                            <name>RELION</name>
                            <version>3.1</version>
                        </software>
                    </software_list>
                </final_angle_assignment>
            </singleparticle_processing>
        </structure_determination>
    </structure_determination_list>
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        <file>emd_71506.map.gz</file>
        <symmetry>
            <space_group>1</space_group>
        </symmetry>
        <data_type>IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)</data_type>
        <dimensions>
            <col>320</col>
            <row>320</row>
            <sec>320</sec>
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            <sec>0</sec>
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        <spacing>
            <x>320</x>
            <y>320</y>
            <z>320</z>
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        <cell>
            <a units="Å">266.56</a>
            <b units="Å">266.56</b>
            <c units="Å">266.56</c>
            <alpha units="deg">90.0</alpha>
            <beta units="deg">90.0</beta>
            <gamma units="deg">90.0</gamma>
        </cell>
        <axis_order>
            <fast>X</fast>
            <medium>Y</medium>
            <slow>Z</slow>
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        <statistics>
            <minimum>-0.012028912</minimum>
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            <average>0.00017706028</average>
            <std>0.0015131274</std>
        </statistics>
        <pixel_spacing>
            <x units="Å">0.833</x>
            <y units="Å">0.833</y>
            <z units="Å">0.833</z>
        </pixel_spacing>
        <contour_list>
            <contour primary="true">
                <level>0.009</level>
                <source>AUTHOR</source>
            </contour>
        </contour_list>
        <label>::::EMDATABANK.org::::EMD-71506::::</label>
        <annotation_details>DuIS local Bot map</annotation_details>
    </map>
    <interpretation>
        <modelling_list>
            <modelling>
                <initial_model>
                    <access_code>8ebt</access_code>
                    <chain>
                        <source_name>PDB</source_name>
                        <initial_model_type>experimental model</initial_model_type>
                    </chain>
                    <details>C7CAD</details>
                </initial_model>
                <initial_model>
                    <access_code>6sxa</access_code>
                    <chain>
                        <source_name>PDB</source_name>
                        <initial_model_type>experimental model</initial_model_type>
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                    <details>XPF/ERCC1</details>
                </initial_model>
                <initial_model>
                    <access_code>1l1o</access_code>
                    <chain>
                        <source_name>PDB</source_name>
                        <initial_model_type>experimental model</initial_model_type>
                    </chain>
                    <details>RPA trimerization core</details>
                </initial_model>
                <refinement_protocol>AB INITIO MODEL</refinement_protocol>
                <refinement_space>REAL</refinement_space>
            </modelling>
        </modelling_list>
        <half_map_list>
            <half_map format="CCP4" size_kbytes="131073">
                <file>emd_71506_half_map_1.map.gz</file>
                <symmetry>
                    <space_group>1</space_group>
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                <dimensions>
                    <col>320</col>
                    <row>320</row>
                    <sec>320</sec>
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                    <col>0</col>
                    <row>0</row>
                    <sec>0</sec>
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                <spacing>
                    <x>320</x>
                    <y>320</y>
                    <z>320</z>
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                <cell>
                    <a units="Å">266.56</a>
                    <b units="Å">266.56</b>
                    <c units="Å">266.56</c>
                    <alpha units="deg">90.0</alpha>
                    <beta units="deg">90.0</beta>
                    <gamma units="deg">90.0</gamma>
                </cell>
                <axis_order>
                    <fast>X</fast>
                    <medium>Y</medium>
                    <slow>Z</slow>
                </axis_order>
                <statistics>
                    <minimum>-0.018590715</minimum>
                    <maximum>0.044084463</maximum>
                    <average>0.00017651977</average>
                    <std>0.0024569556</std>
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                <pixel_spacing>
                    <x units="Å">0.833</x>
                    <y units="Å">0.833</y>
                    <z units="Å">0.833</z>
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                <contour_list>
                    <contour primary="true">
                        <source>AUTHOR</source>
                    </contour>
                </contour_list>
                <label>::::EMDATABANK.org::::EMD-71506::::</label>
                <annotation_details>DuIS local Bot half1 map</annotation_details>
            </half_map>
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                <file>emd_71506_half_map_2.map.gz</file>
                <symmetry>
                    <space_group>1</space_group>
                </symmetry>
                <data_type>IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)</data_type>
                <dimensions>
                    <col>320</col>
                    <row>320</row>
                    <sec>320</sec>
                </dimensions>
                <origin>
                    <col>0</col>
                    <row>0</row>
                    <sec>0</sec>
                </origin>
                <spacing>
                    <x>320</x>
                    <y>320</y>
                    <z>320</z>
                </spacing>
                <cell>
                    <a units="Å">266.56</a>
                    <b units="Å">266.56</b>
                    <c units="Å">266.56</c>
                    <alpha units="deg">90.0</alpha>
                    <beta units="deg">90.0</beta>
                    <gamma units="deg">90.0</gamma>
                </cell>
                <axis_order>
                    <fast>X</fast>
                    <medium>Y</medium>
                    <slow>Z</slow>
                </axis_order>
                <statistics>
                    <minimum>-0.018427366</minimum>
                    <maximum>0.044576757</maximum>
                    <average>0.00017754847</average>
                    <std>0.00243669</std>
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                <pixel_spacing>
                    <x units="Å">0.833</x>
                    <y units="Å">0.833</y>
                    <z units="Å">0.833</z>
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                <contour_list>
                    <contour primary="true">
                        <source>AUTHOR</source>
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                </contour_list>
                <label>::::EMDATABANK.org::::EMD-71506::::</label>
                <annotation_details>DuIS local Bot half2 map</annotation_details>
            </half_map>
        </half_map_list>
    </interpretation>
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