2025-12-24 REL RCSB INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY RCSB RCSB 2025-07-03 2025-12-24 2025-12-24 2025-12-24 National Institutes of Health/National Cancer Institute (NIH/NCI) R01 CA285227 United States Negative stain EM map of EBV glycoprotein gH/gL in complex with glycoprotein gp42 and HLA-DR1 Beta chain Lang K Duy M Pancera M Viral Protein, Complex. Antibody, EBV, IMMUNE SYSTEM Chan CB Lang K Davis AR Wan YH Aldridge NT Kher G Scharffenberger SC Hardy SR Iureniev R Giltiay NV Edwards KR Radtke S Kiem HP Pancera M McGuire A Genetically protective human EBV-neutralizing mAbs targeting multiple receptor-binding sites mAbs elicited in transgenic mice To Be Published 0353 EMDB EMD-71589 associated EM volume Co-expressed EBV glycoprotein gHgL Complex 1:1 with gp42, then complex 1:1 with HLA-DR1 BETA CHAIN Co-expressed EBV glycoprotein gHgL Complex 1:1 with gp42, then complex 1:1 with HLA-DR1 BETA CHAIN 0 1 2 3 4 0.148625 Surface Glycoprotein gH human gammaherpesvirus 4 B95-8 Homo sapiens LEVO MQLLCVFCLVLLWEVGAASLSEVKLHLDIEGHASHYTIPWTELMAKVPGLSPEALWREANVTEDLASMLNRYKLIYKTSGTLGIALAEPVDIPAVSEGSMQVDASKVHPGVISGLNSPACMLSAPLEKQLFYYIGTMLPNTRPHSYVFYQLRCHLSYVALSINGDKFQYTGAMTSKFLMGTYKRVTEKGDEHVLSLVFGKTKDLPDLRGPFSYPSLTSAQSGDYSLVIVTTFVHYANFHNYFVPNLKDMFSRAVTMTAASYARYVLQKLVLLEMKGGCREPELDTETLTTMFEVSVAFFKVGHAVGETGNGCVDLRWLAKSFFELTVLKDIIGICYGATVKGMQSYGLERLAAMLMATVKMEELGHLTTEKQEYALRLATVGYPKAGVYSGLIGGATSVLLSAYNRHPLFQPLHTVMRETLFIGSHVVLRELRLNVTTQGPNLALYQLLSTALCSALEIGEVLRGLALGTESGLFSPCYLSLRFDLTRDKLLSMAPQEATLDQAAVSNAVDGFLGRLSLEREDRDAWHLPAYKCVDRLDKVLMIIPLINVTFIISSDREVRGSALYEASTTYLSSSLFLSPVIMNKCSQGAVAGEPRQIPKIQNFTRTQKSCIFCGFALLSYDEKEGLETTTYITSQEVQNSILSSNYFDFDNLHVHYLLLTTNGTVMEIAGLYEERAHVVLAIILYFIAFALGIFLVHKIVMFFLHHHHHH P03231 Surface Glycoprotein gL human gammaherpesvirus 4 B95-8 Homo sapiens LEVO MRAVGVFLAICLVTIFVLPTWGNWAYPCCHVTQLRAQHLLALENISDIYLVSNQTCDGFSLASLNSPKNGSNQLVISRCANGLNVVSFFISILKRSSSALTGHLRELLTTLETLYGSFSVEDLFGANLNRYAWHRGG P03212 Surface Glycoprotein gp42 human gammaherpesvirus 4 B95-8 Homo sapiens LEVO MVSFKQVRVPLFTAIALVIVLLLAYFLPPRVRGGGRVAAAAITWVPKPNVEVWPVDPPPPVNFNKTAEQEYGDKEVKLPHWTPTLHTFQVPQNYTKANCTYCNTREYTFSYKGCCFYFTKKKHTWNGCFQACAELYPCTYFYGPTPDILPVVTRNLNAIESLWVGVYRVGEGNWTSLDGGTFKVYQIFGSHCTYVSKFSTVPVSHHECSFLKPCLCVSQRSNSHHHHHH P03205 HLA class II histocompatibility antigen, DRB1 beta chain Homo sapiens Homo sapiens LEVO MLLVNQSHQGFNKEHTSKMVSAIVLYVLLAAAAHSAFAADPGPVSKMRMATPLLMQAGNSGGGSLVPRGSGGGGSGDTRPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKSRGGLEVLFQGPVDGGGGGRIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHHHHHHH P01911 singleParticle particle 7.5
1x TBS
 NEGATIVE Uranyl Formate
2% Uranyl Formate
 TFS TALOS L120C FLOOD BEAM BRIGHT FIELD LAB6 120 70.0 2.0 0.3 2.0 96000.0 NITROGEN FEI CETA (4k x 4k) 40.0 1 NONE 11.62 FSC 0.143 CUT-OFF cryoSPARC 4.7.0 3651 MAXIMUM LIKELIHOOD cryoSPARC 4.7.0 MAXIMUM LIKELIHOOD cryoSPARC 4.7.0 emd_71589.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 90 90 90 0 0 0 90 90 90 404.47998 404.47998 404.47998 90.0 90.0 90.0 X Y Z -5.2652726 15.694203 0.007926376 0.43327782 4.494222 4.494222 4.494222 1.23 AUTHOR emd_71589_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 256 256 256 0 0 0 256 256 256 404.48 404.48 404.48 90.0 90.0 90.0 X Y Z -3.2074385 4.0933294 0.0016221596 0.32821885 1.58 1.58 1.58 AUTHOR emd_71589_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 256 256 256 0 0 0 256 256 256 404.48 404.48 404.48 90.0 90.0 90.0 X Y Z -2.6016078 3.9022105 0.0016874495 0.3286311 1.58 1.58 1.58 AUTHOR