2026-03-18 REL RCSB INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY RCSB RCSB 2025-10-12 2026-03-18 2026-03-18 2026-03-18 National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) R01GM139034 United States National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) R35GM158090 United States Local refinement of Fab-14/SARS-CoV-2 D614G spike complex, Mode I Wang Y Hu Y Leiman P Xie X SARS-CoV-2, neutralizing antibody, VIRAL PROTEIN Wang Y Hu Y Ku Z Yeung J Zou J Woodson M Prokhorov N Knyazhanskaya E Zhao H Sherman M An Z Carroll S Shi P-Y Leiman P Xie X Neutralization of SARS-CoV-2 by IgM-14 via Engagement of Two Distinct Spike Epitopes To Be Published 0353 9ynr FULLOVERLAP EMDB EMD-73228 associated EM volume
Local refinement of Fab-14/SARS-CoV-2 D614G spike complex, Mode I
 Local refinement of Fab-14/SARS-CoV-2 D614G spike complex, Mode I Local refinement of Fab-14/SARS-CoV-2 D614G spike complex, Mode I 0 1 2 3
Fab-14 binds to 2-down-RBD
Homo sapiens Spike glycoprotein Severe acute respiratory syndrome coronavirus 2 0.142361391 2 Homo sapiens LEVO MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAVHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPC NGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVPVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPGSASSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGF NFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALN TLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDL QELGKYEQGSGYIPEAPRDGQAYVRKDGEWVLLSTFLGRSLEVLFQGPGHHHHHHHHSAWSHPQFEKGGGSGGGGSGGSA WSHPQFEK A0A7U0LU78 Fab-14 heavy chain Homo sapiens 0.025583445 1 Homo sapiens LEVO EVQLQQSGPGLVKPSQTLSLTCAISGDSVSSNSAAWNWIRQSPSRGLEWLGRTYYRSKWYNDYAVSVKSRITINPDTSKN QFSLQLNSVTPEDTAVYYCAREEQQLVHDYYYYGMDVWGQGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDY FPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTH Fab-14 light chain Homo sapiens 0.022518879 1 Homo sapiens LEVO QAVVTQPASVSGSPGQSITISCTGTSSDIGAYNYISWYQQHPGKAPKLIIYEVSNRPSGISYRFSGSKSGNTASLTISGL QAEDEANYYCSSYAGSISFGGGTKVTVLQPKANPTVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADGSPVKAGV ETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS 2-acetamido-2-deoxy-beta-D-glucopyranose 0.000221208 5 NAG singleParticle particle 0.3 8.0 2.0 Tris tris (hydroxymethyl) aminomethane 200.0 NaCl sodium chloride Quantifoil R2/2 COPPER ETHANE 95 295 LEICA EM GP TFS KRIOS SPOT SCAN DIFFRACTION FIELD EMISSION GUN 300 1.0 2.5 10500.0 NITROGEN GATAN K3 (6k x 4k) 43.17 1 PHASE FLIPPING AND AMPLITUDE CORRECTION 3.55 FSC 0.143 CUT-OFF cryoSPARC 113755 MAXIMUM LIKELIHOOD MAXIMUM LIKELIHOOD emd_73228.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 480 480 480 0 0 0 480 480 480 402.67203 402.67203 402.67203 90.0 90.0 90.0 X Y Z -0.4038808 0.87585 -0.00031962295 0.013128646 0.8389 0.8389 0.8389 0.1 AUTHOR emd_73228_additional_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 480 480 480 0 0 0 480 480 480 402.67203 402.67203 402.67203 90.0 90.0 90.0 X Y Z -0.0018043753 2.4882917 0.00031111413 0.0137525285 0.8389 0.8389 0.8389 AUTHOR map processed by DeepEMhancer emd_73228_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 480 480 480 0 0 0 480 480 480 402.67203 402.67203 402.67203 90.0 90.0 90.0 X Y Z -0.9032994 1.1462291 0.0001361276 0.10613454 0.8389 0.8389 0.8389 AUTHOR emd_73228_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 480 480 480 0 0 0 480 480 480 402.67203 402.67203 402.67203 90.0 90.0 90.0 X Y Z -0.8579037 1.2256889 0.00014263592 0.107068054 0.8389 0.8389 0.8389 AUTHOR half map B