2024-03-13 REL RCSB RCSB RCSB 2018-04-16 2018-05-30 2018-10-17 2024-03-13 Thermostablilized dephosphorylated chicken CFTR Fay JF Riordan JR CFTR, MEMBRANE PROTEIN Fay JF Aleksandrov LA Jensen TJ Cui LL Kousouros JN He L Aleksandrov AA Gingerich DS Riordan JR Chen JZ Cryo-EM Visualization of an Active High Open Probability CFTR Anion Channel. Biochemistry US 57 6234 6246 2018 30281975 doi:10.1021/acs.biochem.8b00763 1520-4995 0033 BICHAW EMD-7794 other EM volume 6d3r FULLOVERLAP CFTR CFTR 0 1 Gallus gallus Cystic fibrosis transmembrane conductance regulator Gallus gallus 0.162637438 1 Cricetinae LEVO MQRSPLEKANIFSKLFFRWTKPILKKGYRQRLELSDIYQIPSADSADNLSEKLEREWDRELATSKKKPKLINALRRCFFW KFMFYGILLYLGEVTKSVQPLLLGRIIASYDPDNSSERSIAYYLGIGLCLLFLVRTLLIHPSIFGLHHIGMQIRIALFSL IYKKTLKLSSKVLDKISTGQLVSLLSNNLNKFDEGLALAHFVWIAPLQVALLMGLLWDMLQASAFAGLAFLIVMAFFQAW LGQMMMKYRDKRAGKINERLVITSEIIENIQSVKAYCWEDAMEKMIESLRETELKLTRKAAYVRYFNSSAFFFSGFFVVF LAVVPYAVTKGIILRKIFTTISFCIVLRMTVTRQFPGSVQTWYDSIGAINKIQDFLLKEEYKALEYNLTTTGVEVDKVTA FWDEHASPVLQDINFKIEKGELLAVSGSTGSGKTSLLMLIMGELEPSEGKIKHSGRISFSPQVSWIMPGTIKENIIFGVS YDEYRYKSVIQACQLEEDILKFPDKDYTVLGEGGIILSGGQRARISLARAVYKDADLYLMDSPFGYLDIFTEKEIFESCV CKLMANKTRILVTSKLEHLKIADKILILHEGSCYFYGTFSELQGQRPDFSSELMGFDSFDQFSAERRNSIITETLRRFSF EGESMGSRNEMKKQSFKQTSDFNDKRKNSIIINPLNAGRKLSIMQKNGTQVNGLEDGHIDSPERRISLVPDLEQGDVGLP RSNMLNSDHMLQSRRRQSVLSLMTGTSVNQGPHVSKKGSTSFRKMSVVPQTNLSSEIDIYTRRLSRDSILDITDEINEED LKECFTDDAESMGTVTTWNTYFRYITIHKSLIFVLILCVTIFLLEVAASLVLLLFLQKAAQINATQPENATSDNPPVIIT DTSSYYMIYIYVGIADTLLAMGIFRGLPLVHTLITVSKTLHQKMVHAVLYAPMSTFNSLKAGGILNRFSKDTAILDDLLP LTVFDLIQLILIVIGAITVVSILQPYIFLASVPVIAAFIVLRAYFLHTSQQLKQLESEARSPIFTHLVTSLKGLWTLRAF GRQPYFETLFHKALNLHTANWFLYLSTLRWFQMRIEMIFVVFFSAVAFISIITTGDGPGRVGIILTLAMNIMGTLQWAVN SSIDVDSLMRSVSRIFKFIDMPTEEMKTIKPQKNNQFSDALIIENRHVKDEKNWPSGGQMTVTDLTARYTEGGTAVLENI SFSISSGQTVGLLGRTGSGKSTLLFAFLRLLNTEGDIQIDGVSWNTVSLQQWRKAFGVIPQKVFIFSGTFRKNLDPYGQW NDEEIWKVAEEVGLKSVIEQFPGQLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPITSQVIRKTLKH AFADCTVVLSESRLEAILECQRFLVIEDNKMRQYESIQKLLSEKSSLRQSGSGGGGGGSLEVLFQGDHHHHHHHHHH 3.6.3.49 ADENOSINE-5'-TRIPHOSPHATE 0.000507181 2 ATP singleParticle particle 7.4 ETHANE FEI TITAN KRIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 GATAN K2 SUMMIT (4k x 4k) SUPER-RESOLUTION 48.0 1 4.3 FSC 1/2 BIT CUT-OFF cryoSPARC 30219 OTHER cryoSPARC OTHER cryoSPARC emd_7793.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 400 400 400 0 0 0 400 400 400 275.46234 275.46234 275.46234 90.0 90.0 90.0 X Y Z -0.58422506 1.126942 0.0034539183 0.035053395 0.68865585 0.68865585 0.68865585 0.28 AUTHOR Sharpened SuperRes PPase-treated chTS map w/o filter by local resolution emd_7793_msk_1.map emd_7793_additional_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 400 400 400 0 0 0 400 400 400 275.4624 275.4624 275.4624 90.0 90.0 90.0 X Y Z -1.2101434 1.5088767 0.0024082235 0.032538734 0.68865603 0.68865603 0.68865603 AUTHOR Sharpened SuperRes PPase-treated chTS map w/ filter by local resolution emd_7793_additional_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 200 200 200 0 0 0 200 200 200 275.462 275.462 275.462 90.0 90.0 90.0 X Y Z -0.5548258 1.6118646 0.0108718965 0.07767029 1.37731 1.37731 1.37731 AUTHOR Binned PPase-treated chTS map emd_7793_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 400 400 400 0 0 0 400 400 400 275.4624 275.4624 275.4624 90.0 90.0 90.0 X Y Z -1.785315 1.7291716 0.0026791522 0.20831089 0.68865603 0.68865603 0.68865603 AUTHOR raw half map A emd_7793_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 400 400 400 0 0 0 400 400 400 275.4624 275.4624 275.4624 90.0 90.0 90.0 X Y Z -2.0461073 1.6817459 0.0026594386 0.20827527 0.68865603 0.68865603 0.68865603 AUTHOR raw half map B